... in the development of the afferent innervation of the organ of Corti: (1) neurite growth and extension of both classes of afferents to all hair cells (E18-P0);(2) neurite refinement, with formation of the outer spiral bundles innervating outer hair cells (P0-P3); (3) neurite retraction and synaptic pruning...

... Center for General and Tumor Immunology,Hadassah Medical School, Jerusalem, Israel 12 11 2003 © 2004. 2004 Rhombic lip Cerebellum Cerebellar granule cells Neurite Notch Delta Jagged Hes Knockout Mouse The highly ordered cytoarchitecture and the relative simplicity...

... processes, are thought to accomplish this navigation through receptors that recognize guidance cues and modulate growth accordingly. In Drosophila , several receptor tyrosine phosphatases (rPTPs), including DLAR, have been shown to participate in directing neurite outgrowth. As yet, however, it is not known...

.... Fredette and B. Ranscht (1994) J. Neurosci . 14, 7331-7346), and therefore, the ability of T-cadherin to inhibit neurite growth was tested in vitro. T-cadherin inhibited neurite extension from select neuron populations both as a substratum, and as a soluble recombinant protein. Anti-T-cadherin antibodies...

... and elongation of neurites from PC 12 cells. Results presented here demonstrate that reagents that specifically alter galtase activity modulate the rate of neurite outgrowth from chick dorsal root ganglia on substrata coated with the large extracellular matrix glycoprotein, laminin (LN), a known substrate...

...James Cohen; Victor Nurcombe; Peter Jeffrey; David Edgar ABSTRACT The ability of chick retinal ganglion cells (RGCs) to extend neurites on tissue culture substrata of the extracellular matrix protein laminin is lost during embryonic development. In order to establish the mechanism responsible...