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Keywords: neural tube development
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Journal Articles

Axial elongation of caudalized human organoids mimics aspects of neural tube development

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Ashley R. G. Libby, David A. Joy, Nicholas H. Elder, Emily A. Bulger, Martina Z. Krakora, Eliza A. Gaylord, Frederico Mendoza-Camacho, Jessica C. Butts, Todd C. McDevitt
Journal: Development
Development (2021) 148 (12): dev198275.
https://doi.org/10.1242/dev.198275
Published: 18 June 2021
..., enabling them to recapitulate aspects of the morphological and temporal gene expression patterns of neural tube development. Elongating organoids consist largely of neuroepithelial compartments and contain TBXT + SOX2 + neuro-mesodermal progenitors in addition to PAX6 + NES + neural progenitors. A critical...
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Includes: Supplementary data
Journal Articles

The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate

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Mirella Dottori, Michael K. Gross, Patricia Labosky, Martyn Goulding
Journal: Development
Development (2001) 128 (21): 4127–4138.
https://doi.org/10.1242/dev.128.21.4127
Published: 1 November 2001
... cells from neural tube progenitors. *Author for correspondence (e-mail: [email protected]) 27 7 2001 © 2001. 2001 Winged-helix genes Foxd3 Neural crest specification Neural tube development Chick Mouse The neural crest is a specialized population of cells...
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Journal Articles

Hox-4 gene expression in mouse/chicken heterospecific grafts of signalling regions to limb buds reveals similarities in patterning mechanisms

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J.-C. Izpisúa-Belmonte, J. M. Brown, A. Crawley, D. Duboule, C. Tickle
Journal: Development
Development (1992) 115 (2): 553–560.
https://doi.org/10.1242/dev.115.2.553
Published: 1 June 1992
... development gastrulation neural tube development mouse/chicken grafts pattern formation Hox-4 Hox-4 genes are good candidates to encode position in vertebrate limbs. 5’ members of the Hox-4 complex (Hox-4 . 4 to Hox-4 . 8) are expressed in developing limb buds in a series of overlapping...
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