...Benjamin Charvet; Alexandre Guiraud; Marilyne Malbouyres; Daniela Zwolanek; Emilie Guillon; Sandrine Bretaud; Catherine Monnot; Jörg Schulze; Hannah L. Bader; Bruno Allard; Manuel Koch; Florence Ruggiero The myotendinous junction (MTJ) is the major site of force transfer in skeletal muscle...

...Beatriz Estrada; Stephen S. Gisselbrecht; Alan M. Michelson The molecular mechanisms underlying muscle guidance and formation of myotendinous junctions are poorly understood both in vertebrates and in Drosophila . We have identified a novel gene that is essential for Drosophila embryonic muscles...

... cell types, their extracellular matrix (ECM)ligands have been only partially characterized. We show that the ECM protein Thrombospondin (Tsp), produced by tendon cells, is essential for the formation of the integrin-mediated myotendinous junction. Tsp expression is induced by the tendon-specific...

.... 1A ) or bulbous ( Fig. 1B ) in shape. The region of the tendon contained many fibroblasts, but little organised extracellular material. The dense bundles of banded collagen fibrils which are prominent at adult myotendinous junctions, were not observed. Extracellular material was generally...