... primordium (ASP) and myoblasts. Hh distributes in concentration gradients in the anterior compartment of the wing disc, ASP and myoblasts, and activates genes in each tissue. Some targets of Hh signal transduction are common to the disc, ASP and myoblasts, whereas others are tissue-specific. Signaling...

...Mar Ruiz-Gómez; Nikola Coutts; Maximiliano L. Suster; Matthias Landgraf; Michael Bate We report a new gene, myoblasts incompetent , essential for normal myogenesis and myoblast fusion in Drosophila . myoblasts incompetent encodes a putative zinc finger transcription factor related to vertebrate...

...Akinao Nose; Takako Isshiki; Masatoshi Takeichi ABSTRACT The somatic musculature in the abdominal hemisegments of Drosophila consists of 30 uniquely identifiable muscle fibers. Previous studies have suggested that the muscle diversity originates in a special class of myoblasts, called muscle...

...Sudipto Roy; K. VijayRaghavan ABSTRACT We have investigated the roles of homeotic selector genes in the migration and fusion of myoblasts, and in the differentiation of adult muscle fibres of Drosophila . Altering intrinsic homeotic identities of myoblasts does not affect their segment-specific...

... in the cells at the ventrolateral edge of the somitic dermomyotome. * Author for correspondence 19 04 1996 © 1996 by Company of Biologists 1996 Met receptor tyrosine kinase hepatocyte growth factor/scatter factor somites Splotch Pax-3 cell migration dermomyotome myoblasts...

... is detected, 10 hours after puparium formation, in myoblasts that will form the indirect flight muscles. The early events of muscle development are normal in ewg mutants. However, a few hours after the onset of erect wing expression in myoblasts, defects are seen in the developing indirect flight muscles...

... and induce myoblast maturation in vitro, depending on the culture conditions. Whether the type I or type II TGF-β receptor mediates the various TGF-β effects on myogenesis is not known. In the present study, C2C12 myoblasts were transfected with an expression vector for a truncated type II TGF-β receptor...

...-specific marker genes or myogenic transcription factors until they reach their destination in the limbs. Here, we demonstrate by in situ hybridization that myogenic cells in somites and a population of presumably migratory muscle precursor cells in somatopleural tissue as well as myoblasts...

... identified two enhancer-containing regions of 1.5 and 1.0 kb in length, 5 of the transcribed sequences, which independently directed expression in the embryo to either the mid/hindbrain region or mandibular myoblasts, respectively. The 1.5 kb fragment contains the most anterior neural enhancer and the 1.0 kb...

... mechanism of myogenic cell diversification. In particular, embryonic, fetal and newborn mouse myoblasts express the MRFs in very similar patterns, though these cells have distinct properties as myoblasts and express diverse myogenic programs upon differentiation. What mechanisms besides simple differential...

... of sympathoadrenal cells around the dorsal aorta and later in the dorsal root ganglia shortly after gangliogenesis. Immunoreactivity appears on pro-spective myotomal cells as the somites delaminate into the dermomyotome and sclerotome, remaining prominent on myoblasts and differentiated muscle at all stages...

...M. J. Duxson; Y. Usson; A. J. Harris ABSTRACT The distribution of secondary myotubes and undifferentiated mononucleated cells (presumed to be myoblasts) within foetal IVth lumbrical muscles of the rat was analyzed with serial section electron microscopy. In all myotube clusters for which...

... by a nearly synchronous fusion of myoblasts with similar birthdates. In contrast, secondary myotubes form in a progressive fashion, myoblasts with asynchronous birthdates fusing laterally with secondary myotubes at random positions along their length. These later-differentiating myoblasts do not fuse...

...J. J. Ross; M. J. Duxson; A. J. Harris ABSTRACT Numbers of myoblasts, primary myotubes and secondary myotubes in developing rat embryo hindlimb IVth lumbrical muscles were counted at daily intervals up until the time of birth, using electron mi-croscopy. Motoneurone death at the spinal cord level...