... in the fusion process; by contrast, the molecular basis of myoblast fusion during vertebrate embryogenesis remains poorly characterised. A key component of the intracellular fusion pathway in Drosophila is the protein encoded by the myoblast city (mbc) gene, a close homologue of the vertebrate protein dedicator...

...Emma Rushton; Rachel Drysdale; Susan M. Abmayr; Alan M. Michelson; Michael Bate ABSTRACT We have used mutations in the newly identified gene myoblast city to investigate the founder cell hypothesis of muscle development in Drosophila melanogaster . In embryos mutant for myoblast city the fusion...