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Keywords: myf5
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Journal Articles
Journal: Development
Development (2020) 147 (8): dev184689.
Published: 28 April 2020
... to promote dorsal mesoderm formation, but their role in myogenesis has been unclear. Using zebrafish, we show that dorsally derived Fgf signals act through Tbx16 and Tbxta to induce slow and fast trunk muscle precursors at distinct dorsoventral positions. Tbx16 binds to and directly activates the myf5...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (1): 83–94.
Published: 1 January 2017
... http://www.biologists.com/user-licence-1-1/ Summary: Analysis of PDGFRα gain-of-function mutant mice demonstrates a role in balancing the expansion of fibroblast and adipocyte lineages before birth. Platelet-derived growth factor Adipocyte Lipodystrophy Myf5 Cell fate Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (8): 1740–1750.
Published: 15 April 2013
... regulatory factors Myf5 and MyoD (also known as Myod1 ) ( Buckingham, 2001 ). Subsequently, the central DM dissociates producing dermis and Pax3- and Pax7-positive myoblasts that remain mitotically active within the myotome and share a common lineage with dermal cells ( Ben-Yair and Kalcheim, 2005...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (24): 4536–4548.
Published: 15 December 2012
... ). Delta 1-activated notch inhibits muscle differentiation without affecting Myf5 and Pax3 expression in chick limb myogenesis . Development 127 , 5213 – 5224 . Dong Z. , Yang N. , Yeo S. Y. , Chitnis A. , Guo S. ( 2012 ). Intralineage directional notch signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (5): 958–967.
Published: 1 March 2012
...Natalia Moncaut; Joe W. Cross; Christine Siligan; Annette Keith; Kevin Taylor; Peter W. J. Rigby; Jaime J. Carvajal The specification of the skeletal muscle lineage during craniofacial development is dependent on the activity of MYF5 and MYOD, two members of the myogenic regulatory factor family...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (14): 2935–2945.
Published: 15 July 2011
... and differentiation into fibers, demonstrating that regulation of pioneer patterning is somite-intrinsic. Furthermore, pioneer myoblasts express Robo2 downstream of MyoD and Myf5, whereas the dermomyotome and caudal sclerotome express Slit1. Loss of Robo2 or of sclerotome-derived Slit1 function perturbed both...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (20): 3495–3504.
Published: 15 October 2009
... regulate early myotome formation in the mouse embryo. Development 133 , 1635 -1644. Borello, U., Berarducci, B., Murphy, P., Bajard, L., Buffa, V.,Piccolo, S., Buckingham, M. and Cossu, G. ( 2006 ). The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (3): 403–414.
Published: 1 February 2009
...Yaniv Hinits; Daniel P. S. Osborn; Simon M. Hughes Myogenic regulatory factors of the Myod family (MRFs) are transcription factors essential for mammalian skeletal myogenesis. However,the roles of each gene in myogenesis remain unclear, owing partly to genetic linkage at the Myf5/Mrf4 locus...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (14): 2731–2745.
Published: 15 July 2006
... ( Mahmood et al., 1995 ); Lbx1 ( Dietrich et al., 1998 ); Myf5 ( Saitoh et al.,1993 ); MyoR ( von Scheven et al., 2006 ); Paraxis ( Sosic et al., 1997 ); Shh ( Johnson et al.,1994 ). Upon in-situ hybridisation, whole-mount immunohistochemistry was carried out according to Guthrie and Lumsden...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (9): 1635–1644.
Published: 1 May 2006
... laminin matrix occurs as epaxial myogenic precursor cells enter the myotome. Most Myf5-positive and myogenin-negative myogenic precursor cells localise near assembled laminin, while myogenin-expressing cells are located either away from this matrix or in areas where it is being assembled. In Myf5 nlacZ...
Journal Articles
Journal: Development
Development (2006) 133 (6): 1101–1112.
Published: 15 March 2006
... Epithelial to mesenchymal transition Muscle Myod Myf5 Pax3 Pax7 Somite The embryonic myotome is the source of all epaxial and hypaxial skeletal muscles. The mechanisms underlying myotome development were recently reevaluated ( Brent and Tabin,2002 ; Buckingham,2001 ; Hollway...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (2): 195–208.
Published: 15 January 2006
... as a stock solution in DEPC-treated H 2 O at a concentration of 1 mg/ml. Working solutions of lbx1,myoD, myf5, myoD + lbx1 and myf5 + lbx1 were diluted to 0.1 mg/ml in DEPC-treated H 2 O. Approximately 4 nl of each mRNA solution was injected into one cell at the two-cell stage. Injections were...
Journal Articles
Journal: Development
Development (2005) 132 (3): 515–528.
Published: 1 February 2005
... development in mouse mutants with genetically disrupted muscle or cartilage development. Through analysis of embryos carrying null mutations in Myf5 and Myod1 , hence lacking both muscle progenitors and differentiated muscle, we identify an essential role for the specified myotome in axial tendon development...
Journal Articles
Journal: Development
Development (2005) 132 (2): 345–357.
Published: 15 January 2005
... in the Myf5 epaxial somite (ES)enhancer, is required for the specification of epaxial muscle progenitor cells. Shh signalling is also required for the normal mediolateral patterning of myogenic cells within the somite. In this study, we investigate the role and the transcriptional activities of Gli proteins...
Journal Articles
Journal: Development
Development (2004) 131 (16): 3967–3980.
Published: 15 August 2004
... and differentiation of graft-derived cells were assayed using QCPN and QH1 antibodies to identify all quail cells and quail endothelial cells, respectively. Chimeric embryos were assayed for expression of myf5, myod, paraxis and lbx1 , and the synthesis of myosin heavy chain (MyHC), between 1 and 6 days later (stages...
Journal Articles
Journal: Development
Development (2004) 131 (14): 3249–3262.
Published: 15 July 2004
... somites, it seems there is a block on Hh response that prevents Xshh and Xbhh from promoting differentiation or survival of first wave slow fibres in trunk somites( Fig. 8A , trunk series). In both fish and Xenopus trunk, myf5 expression is highest close to the notochord, whereas myod...
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (20): 4797–4807.
Published: 15 October 2003
... this discrepancy, we have re-addressed this issue, using short-term in vivo microsurgery and culture experiments in chick. Our results show that the initial expression of the muscle-specific markers Myf5 and MyoD is regulated in a mesoderm-autonomous fashion. The reception of a Wnt signal is required for MyoD...
Journal Articles