...) and the slow-twitch muscle pioneers (MPs) are characterised by expression of eng1a , - 1b and - 2a and require the highest levels of Hh for their specification. We have defined a minimal eng2a element sufficient to drive reporter expression specifically in MPs and MFFs. This element binds both Gli2a...

..., muscle pioneers and the primary motoneurons are affected, in addition to the horizontal myoseptum. The horizontal myoseptum is also missing in mutants that lack a notochord. The similarity of the somite phenotype in mutants lacking the notochord and in the you- type mutants suggests that the genes...

... © 1992 by Company of Biologists 1992 Brachydanio rerio fin bud gene expression hindbrain homeodomains jaw muscles midbrain muscle pioneers somites Transcription factors, including homeoproteins, are known to regulate the development of cell fates and patterning in embryos...

... not. The expression in subsets of cerebellar cells, in midbrain nuclei, in muscle pioneers and as mentioned in the previous section, in rostral hindbrain segments may be other examples of such position-dependent specifications underlain by Eng. In each case, the pattern changes in a characteristic fashion along...