... two distinct deletions in the proximal promoter region, resulting in either greatly upregulated or downregulated expression of the entire Dlk1-Dio3 ncRNA cluster. Both mutant lines displayed impaired muscle differentiation along with dysregulated structural gene expression and abnormalities...

... 2020 © 2021. Published by The Company of Biologists Ltd 2021 Summary: Muscle differentiation and regeneration are regulated by an evolutionarily conserved long noncoding RNA that restricts gene expression to coordinate cell state transitions. Muscle differentiation Cell identity...

... of Biologists Ltd 2017 Summary: This Review discusses the mechanisms that underpin the formation of skeletal muscle during development and its recapitulation from pluripotent stem cells in vitro . Skeletal myogenesis Muscle differentiation Paraxial mesoderm Somite Dermomyotome Muscular...

.... , VijayRaghavan K. ( 1998 ). Twist and Notch negatively regulate adult muscle differentiation in Drosophila . Development 125 , 1361 – 1369 . Baker P. W. , Tanaka K. K. , Klitgord N. , Cripps R. M. ( 2005 ). Adult myogenesis in Drosophila melanogaster can proceed independently...

... polarity. These studies provide important in vivo insights into the contribution of FGF signaling events to myogenesis. * Author for correspondence (e-mail: [email protected] ) 31 8 2004 © 2004. 2004 FGF receptor EGL-15 PI3 kinase Signal transduction Muscle differentiation...

.... † Author for correspondence (e-mail: [email protected] ) * These authors contributed equally to the work 24 4 2003 © 2003. 2003 Ca 2+ current Herg Muscle differentiation Myoblast fusion Window current Skeletal muscle formation depends on the fusion...

... 03 03 1999 © 1999 by Company of Biologists 1999 β-Thymosin Zebrafish Neuronal growth Muscle differentiation Actin Antisense injections To reach the appropriate target, axon-extending neurons depend on the ability to rapidly polymerize and depolymerize their cytoskeleton...

...Delphine Duprez; Claire Fournier-Thibault; Nicole Le Douarin ABSTRACT M yogenic R egulatory F actors (MRFs) are a family of transcription factors whose expression in a cell reflects the commitment of this cell to a myogenic fate before any cytological sign of muscle differentiation is detectable...

... chick muscle differentiation. Fetal myogenic cells originating from transgenic mice carrying a lacZ reporter were readily detected in vivo after implantation and their state of differentiation determined with species-specific antibodies to MyoD and myosin heavy chain. When mouse myogenic cells...

... : Editions du CNRS . Rong , P. M. , Teillet , M.-A. , Ziller , C. and Le Douarin , N. M. ( 1992 ). The neural tube/notochord complex is necessary for vertebral but not limb and body wall striated muscle differentiation . Development 115 , 657 – 672 . 10.1242/dev.115.3.657...

... but not trunk muscle. * Author for correspondence 22 12 1993 © 1994 by Company of Biologists 1994 Pax-3 somites notochord muscle differentiation splotch mutation myoD The patterning and differentiation of cells in the somitic mesoderm is an important step...

... was monitored by an antibody to ascidian myosin. Muscle differentiation was observed only when presumptive-epidermis blastomeres were fused with fragments from the posterior region of B4.1 (posterior-vegetal) blastomeres, the normal progenitor of muscle cells. The results indicate that muscle determinants...

... development in situ hybridisation implantation muscle differentiation nervous system mesenchyme Lectins are generally defined as non-enzymatic, non-immunoglobulin proteins, which bind selectively to specific carbohydrate structures ( Goldstein et al., 1980 ). Many of the lectins isolated from...

... and adult rat heart ( Jin and Lin, 1988 ; Dhoot, 1988 ; Saggin et al . 1988 ). cardiac troponin T muscle differentiation muscle regeneration muscle denervation rat embryo skeletal muscle. © 1990 by Company of Biologists 1990 10 07 1990 * Present address: Fidia...

... that contain spindle-specific myosin isoforms all depend on the presence of innervation in prenatal rat muscles. 08 06 1990 © 1990 by Company of Biologists 1990 myosin heavy chains intrafusal muscle fibers muscle differentiation nerve dependence fetal rat ft bungarotoxin...

... the 64-cell embryos (A7.8) did not show any features of muscle differentiation, whereas some isolated A-line cells from the 110-cell embryos (A8.16) developed all three above-mentioned features of muscle cells. This transition was shown to occur during the eighth cell cycle. These results suggest...

...G. Cossu; G. Ranaldi; M. I. Senni; M. Molinaro; E. Vivarelli Mesenchymal cells were isolated from somites and limbs of mouse embryos at different developmental stages. When grown in tissue culture, some of the cells underwent muscle differentiation as indicated by synthesis of sarcomeric myosin...

... University, Tennoji, Osaka 543, Japan 29 04 1987 © 1987 by Company of Biologists 1987 ascidian embryo myoplasm monoclonal antibodies cytoplasmic determinants muscle differentiation Various descriptive and experimental studies since the turn of the century have documented...

... address: Department of Biology, Osaka Kyoiku University, Tennoji, Osaka 543, Japan 26 09 1986 © 1987 by Company of Biologists 1987 ascidian embryo muscle differentiation monoclonal antibody determinants DNA replication The embryological development of ascidians...