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Keywords: muscle
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Journal Articles
Journal: Development
Development (2022) 149 (8): dev199906.
Published: 3 May 2022
... repair by scar formation and the initiation of tissue regeneration. They initially assume inflammatory phenotypes, releasing pro-inflammatory cytokines and removing dead and dying tissue, before entering a reparative stage, replacing dead muscle tissue with a non-contractile scar. In this Review, we...
Journal Articles
Journal Articles
Journal: Development
Development (2021) 148 (5): dev198663.
Published: 9 March 2021
... in Drosophila , however, have begun to reveal new roles of nuclear receptor signaling in peripheral tissues in controlling reproduction. Here, we identified Hormone receptor 4 (Hr4) as an oogenesis regulator required in the ovary and muscles. Global Hr4 knockdown leads to increased germline stem cell (GSC) loss...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (1): dev190868.
Published: 10 January 2021
...Myung-Jun Kim; Michael B. O'Connor ABSTRACT The Myostatin/Activin branch of the TGF-β superfamily acts as a negative regulator of vertebrate skeletal muscle size, in part, through downregulation of insulin/insulin-like growth factor 1 (IGF-1) signaling. Surprisingly, recent studies in Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (23): dev191304.
Published: 13 December 2020
... Nuclear lamina Muscle Nuclear envelope Endoreplication emerges as an important strategy of differentiated cells, enabling them to grow in size or rescue tissue integrity following injury, in a wide range of non-dividing cell types ( Gan et al., 2019 ). Recent experimental studies have proposed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (8): dev184689.
Published: 28 April 2020
...Daniel P. S. Osborn; Kuoyu Li; Stephen J. Cutty; Andrew C. Nelson; Fiona C. Wardle; Yaniv Hinits; Simon M. Hughes ABSTRACT Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation. Fibroblast growth factor (Fgf) signalling cooperates with Tbx transcription factors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (3): dev173104.
Published: 4 February 2019
...Deli Yu; Izumi Oda-Ishii; Atsushi Kubo; Yutaka Satou ABSTRACT Striated muscle cells in the tail of ascidian tadpole larvae differentiate cell-autonomously. Although several key regulatory factors have been identified, the genetic regulatory pathway is not fully understood; comprehensive...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2018) 145 (17): dev159558.
Published: 28 August 2018
... that appears to be essential for efficient inter-membranous exchange of RNA, proteins and ions. We found that the membrane-associated Muscle-specific α2/δ (Ma2/d) subunit of the Ca 2+ channel complex localizes to the SR and T-tubules, and accumulates at the myonuclear surfaces. Furthermore, Ma2/d mutant larval...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4481–4495.
Published: 15 December 2017
.... and Olson , E. N. ( 2017 ). Control of muscle formation by the fusogenic micropeptide myomixer . Science   356 , 323 - 327 . 10.1126/science.aam9361 Bianchi , E. , Doe , B. , Goulding , D. and Wright , G. J. ( 2014 ). Juno is the egg Izumo receptor and is essential...
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (23): 4038–4048.
Published: 1 December 2015
...Peter C. D. Macpherson; Pershang Farshi; Daniel Goldman Muscle denervation resulting from injury, disease or aging results in impaired motor function. Restoring neuromuscular communication requires axonal regrowth and endplate reinnervation. Muscle activity inhibits the reinnervation of denervated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (20): 3512–3518.
Published: 15 October 2015
...Elly Ordan; Talila Volk Coordinated locomotion of an organism relies on the development of proper musculoskeletal connections. In Drosophila , the Slit-Robo signaling pathway guides muscles to tendons. Here, we show that the Slit receptor Roundabout 2 (Robo2) plays a non-cell-autonomous role...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (5): 983–993.
Published: 1 March 2015
...Liora Kutchuk; Anu Laitala; Sharon Soueid-Bomgarten; Pessia Shentzer; Ann-Helen Rosendahl; Shelly Eilot; Moran Grossman; Irit Sagi; Raija Sormunen; Johanna Myllyharju; Joni M. Mäki; Peleg Hasson Muscle is an integrated tissue composed of distinct cell types and extracellular matrix. While much...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2014) 141 (9): 1821–1834.
Published: 1 May 2014
... to the embryo proper, and are subsequently found within the mesenchyme. A subpopulation of these cells, distinct from embryonic macrophages, co-expresses mesenchymal and hematopoietic markers. In addition, hemogenic endothelium-derived cells contribute to skeletal and smooth muscle, and to other mesodermal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (8): 1649–1659.
Published: 15 April 2014
... dynamics in tissue-specific stem cells during conditions of increased tissue turnover remains limited. Using a TetO-H2B-GFP reporter of proliferative history, we identify skeletal muscle stem cell, or satellite cells, that retain (LRC) or lose (nonLRC) the H2B-GFP label. We show in mice that LRCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (2): 355–366.
Published: 15 January 2014
...Eric S. Folker; Victoria K. Schulman; Mary K. Baylies Nuclei are precisely positioned within all cells, and mispositioned nuclei are a hallmark of many muscle diseases. Myonuclear positioning is dependent on Kinesin and Dynein, but interactions between these motor proteins and their mechanisms...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (14): 3040–3050.
Published: 15 July 2013
... by inducing oncogenic KRAS G12D expression at different stages during muscle development. Several zebrafish promoters were used, including the cdh15 and rag2 promoters, which drive gene expression in early muscle progenitors, and the mylz2 promoter, which is expressed in differentiating myoblasts. The tumors...
Includes: Supplementary data