..., London SE1 9RT, UK 17 12 1996 © 1997 by Company of Biologists 1997 nodal mouse gastrulation primitive endoderm chimeras Nodal, a member of the TGFβ family of secreted growth factors, was originally identified due to its close linkage with the 413.d proviral integration...

... that different post-transcriptional mechanisms control Otx2 expression in both layers. * Author for correspondence † Both first authors contributed equally to the work 27 6 1995 © 1995 by Company of Biologists 1995 neural induction Otx2 mouse gastrulation node anterior...

... a positive inductive signal from underlying anterior mesendoderm in the headfold stage embryo ( Ang and Rossant, 1993 ), although En expression did not begin till the early somite stage. Otx2 explant cultures mesoderm tissue interactions retinoic acid mouse gastrulation © 1994 by Company...

... at the mammalian primitive streak. 15 04 1933 © 1993 by Company of Biologists 1993 cell-cell adhesion cell migration mouse gastrulation extracellular matrix Adhesive interactions among cells and between cells and their surrounding extracellular matrix (ECM) are important during...

...: the primary perturbation may be obscured by subsequent defective tissue interactions producing a complex phenotype (see Beddington et al., 1991 ). Brachyury mouse gastrulation embryonic stem cells ...