... that adult muscle precursors (AMPs), the Drosophila muscle stem cells, interact with the motor axons during embryogenesis. AMPs not only hold the capacity to attract the navigating intersegmental (ISN) and segmental a (SNa) nerve branches, but are also mandatory to the innervation of muscles in the lateral...

... the fin at ectopic positions, yet innervate their designated target areas, suggesting that motor axons can select their appropriate fin target area independently of their migration through the plexus. Although foxc1a mutants display topographically correct fin innervation, mutant fin muscles exhibit...

...Julaine Roffers-Agarwal; Laura S. Gammill The segmented trunk peripheral nervous system is generated by ventrally migrating neural crest cells that exclusively invade the anterior sclerotome and differentiate into metameric dorsal root and sympathetic ganglia. Meanwhile, ventral spinal motor axons...

...Julie L. Lefebvre; Fumihito Ono; Cristina Puglielli; Glen Seidner; Clara Franzini-Armstrong; Paul Brehm; Michael Granato Before establishing terminal synapses with their final muscle targets,migrating motor axons form en passant synaptic contacts with myotomal muscle. Whereas signaling through...

... single mutations also cause motor axon phenotypes that selectively affect the SNa nerve. DPTP52F, DPTP10D and DPTP69D have partially redundant roles in regulation of guidance decisions made by axons within the ISN and ISNb motor nerves. §Author for correspondence (e-mail: [email protected]...

...Jing Zhang; Michael Granato ABSTRACT En route to their targets, motor axons encounter choice points at which they select their future path. Experimental studies predict that at each choice point specialized cells provide local guidance to pathfinding motor axons, however, the identity...

...Jörg Zeller; Michael Granato During vertebrate embryogenesis different classes of motor axons exit the spinal cord and migrate on common axonal paths into the periphery. Surprisingly little is known about how this initial migration of spinal motor axons is controlled by external cues. Here, we show...

... Drosophila Nerve Axon guidance Drac1 Rac1 Motor axon Muscle In order to reach appropriate target tissues in the developing embryo, neuronal growth cones must navigate through a complex cellular terrain in response to various guidance cues. This process requires an interplay between information...

... is a negative guidance cue for motor axon projections. * Author for correspondence 03 07 1996 © 1996 by Company of Biologists 1996 axon guidance growth cone repulsion axonogenesis T-cadherin spinal motor neuron motor axon hindlimb neurite mammal The intricate network...

.... As the DRG form and motor axons extend from the ventral neural tube, the sharp discontinuity between versican staining in the posterior and the absence of staining in the anterior half of the sclerotome prevails ( Fig. 3C ). Only in the most rostrally localized somites could versican-specific...

... with AChE in motoneurones), motor axons begin to grow exclusively through the BChE-rich sclerotomal space towards the AChE-activated myotome anlage. On motor axons, AChE detection is significantly retarded. We conclude that the rostrocaudal segmental asymmetry is not restricted to the sclerotomes (which...