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Keywords: morphogen gradient
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Journal Articles
Journal: Development
Development (2021) 148 (7): dev192344.
Published: 6 April 2021
... through grant R35-GM131908. Deposited in PMC for immediate release. References Affolter , M. and Basler , K. ( 2007 ). The Decapentaplegic morphogen gradient: from pattern formation to growth regulation . Nat. Rev. Genet. 8 , 663 - 674 . 10.1038/nrg2166 Akiyama , T...
Journal Articles
Journal: Development
Development (2021) 148 (5): dev191791.
Published: 9 March 2021
...Tanvi Gore; Tamás Matusek; Gisela D'Angelo; Cécile Giordano; Thomas Tognacci; Laurence Lavenant-Staccini; Catherine Rabouille; Pascal P. Thérond ABSTRACT The Hedgehog (Hh) morphogen gradient is required for patterning during metazoan development, yet the mechanisms involved in Hh apical...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (21): dev181487.
Published: 12 November 2019
...Neta Rahimi; Inna Averbukh; Shari Carmon; Eyal D. Schejter; Naama Barkai; Ben-Zion Shilo ABSTRACT Establishment of morphogen gradients in the early Drosophila embryo is challenged by a diffusible extracellular milieu, and by rapid nuclear divisions that occur at the same time. To understand how...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev162792.
Published: 14 September 2018
... ). Cytonemes as specialized signaling filopodia . Development   141 , 729 - 736 . 10.1242/dev.086223 Lander , A. D. ( 2007 ). Morpheus unbound: reimagining the morphogen gradient . Cell   128 , 245 - 256 . 10.1016/j.cell.2007.01.004 Lee , J. L. and Streuli , C. H. ( 2014...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (1): 124–135.
Published: 1 January 2014
... interrogations of the properties of morphogen gradients that instruct patterning. Recent studies of the Drosophila morphogen gradient Bicoid (Bcd), which is required for anterior-posterior (AP) patterning in the early embryo, have uncovered two distinct ways of scaling. Whereas between-species scaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (15): 2730–2739.
Published: 1 August 2012
..., USA ‡ Author for correspondence ( xz4@iupui.edu ) Competing interests statement The authors declare no competing financial interests. 14 5 2012 © 2012. 2012 FGF Heparan sulfate Glycosaminoglycan Lacrimal gland Branching morphogenesis Morphogen gradient Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (22): 4867–4874.
Published: 15 November 2011
...Jitendra S. Kanodia; Yoosik Kim; Raju Tomer; Zia Khan; Kwanghun Chung; John D. Storey; Hang Lu; Philipp J. Keller; Stanislav Y. Shvartsman A crucial issue in studies of morphogen gradients relates to their range: the distance over which they can act as direct regulators of cell signaling, gene...
Journal Articles
Journal: Development
Development (2011) 138 (13): 2741–2749.
Published: 1 July 2011
... (Bcd) morphogen gradient. Using embryos from lines artificially selected for large and small egg volume, we show that large embryos have higher nuclear Bcd concentrations in the anterior than small embryos. This anterior difference leads to scaling properties of the Bcd gradient profiles: in broad...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1923–1933.
Published: 1 June 2008
.... Gurken Egfr Cbl Morphogen gradient Endocytosis Drosophila Morphogens play pivotal roles during many important developmental stages to induce distinct cell fates by forming concentration gradients that provide positional information. The gradient formation is usually controlled...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (23): 5705–5716.
Published: 1 December 2003
..., Hungarian Academy of Sciences, Budapest H-1143, Hungary 13 8 2003 © 2003. 2003 BMP Morphogen gradient SMAD Dorsal-ventral patterning Drosophila Dorsal-ventral (DV) patterning of the Drosophila embryo is a paradigm for understanding the regulation of bone morphogenetic...
Journal Articles
Journal: Development
Development (2003) 130 (9): 1937–1947.
Published: 1 May 2003
.... and Niehrs, C. ( 2001 ). A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus. Development 128 , 4189 -4201. Kim, C. H., Oda, T., Itoh, M., Jiang, D., Artinger, K. B.,Chandrasekharappa, S. C., Driever, W. and Chitnis, A. B. ( 2000 ). Repressor...
Journal Articles
Journal: Development
Development (2003) 130 (8): 1515–1522.
Published: 15 April 2003
... protein and Dpp signal transduction is potentiated by Dally, a cell-surface heparan sulfate proteoglycan, during assembly of several adult tissues. However, the molecular mechanism by which the Dpp morphogen gradient is established and maintained is poorly understood. We show evidence that Dally regulates...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4189–4201.
Published: 1 November 2001
... the Xenopus central nervous system. *Author for correspondence (e-mail: niehrs@dkfz-heidelberg.de ) 2 8 2001 © 2001. 2001 Anteroposterior neuraxis AP β-catenin Gastrulation Head organizer Long-range signalling Morphogen gradient Neural patterning Neuroectoderm Nieuwkoop...
Journal Articles
Journal: Development
Development (1989) 107 (Supplement): 121–131.
Published: 1 April 1989
..., morphogen gradient, retinoic-acid-binding protein. 1. Retinoic acid, a candidate morphogen in the developing vertebrate limb A dominant force in embryonic development is the coordinate expression of the genetic program (David- son, 1986). For example, early insect pattern formation is orchestrated at least...