..., the early Drosophila embryo undergoes rapid cleavage cycles in a lipid-rich environment. Here, we show that mitotic spindle formation, centrosomal maturation, and ER condensation occur with similar time frames in the early syncytium. In a screen for Rab family GTPases that display dynamic function...

... by The Company of Biologists Ltd 2022 Summary: The temporal control of Schwann cell mitotic exit is an essential step that mediates laminin expression in order to drive radial sorting and peripheral myelination. Sil Schwann cell Peripheral nervous system Mitotic spindle MCPH Zebrafish...

...Dan T. Bergstralh; Nicole S. Dawney; Daniel St Johnston The direction in which a cell divides is determined by the orientation of its mitotic spindle at metaphase. Spindle orientation is therefore important for a wide range of developmental processes, ranging from germline stem cell division...

... acceleration on exposure to fibroblast growth factor (FGF), an inhibitor of neuronal differentiation. This study provides a novel, dynamic view of spinal cord neurogenesis and supports a model in which cleavage plane orientation/mitotic spindle position does not assign neuron-generating ability, but functions...

...Kirsten K. Hanson; Ann C. Kelley; Mariann Bienz The chromosomal passenger complex (CPC) is a key regulator of mitosis in many organisms, including yeast and mammals. Its components co-localise at the equator of the mitotic spindle and function interdependently to control multiple mitotic events...

... derived from homozygous fue mothers. In addition,a defect in the formation of chromosomal microtubules prevents mitotic spindle assembly and thus chromosome segregation in fue zygotes. However,centrosomal functions do not appear to be affected in fue embryos,suggesting this mutant blocks a subset...

... and patterning mutants suggests that its localization is not dependent on the correct fate of either the germline or the gut blastomere but is dependent upon correct spatial organization of the embryo. Our results suggest that MES-1 directly positions the developing mitotic spindle and its associated P granules...

...Steven W. Wang; Fred J. Griffin; Wallis H. Clark, Jr ABSTRACT During early cleavages of Sicyonia ingentis embryos, mitotic spindle orientations differ between blastomeres and change in a predictable manner with each successive mitosis. From 2 nd through 7 th cleavages, spindles orient at a 90...

... the mitotic spindles properly for these unequal cell cleavages. * Author for correspondence † Present address: Department of Anatomy and Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA 27 10 1995 © 1996 by Company of Biologists 1996 asymmetric cell...