...Jessica K. Sawyer; Erez Cohen; Donald T. Fox The molecular identities and regulation of cells at interorgan boundaries are often unclear, despite the increasingly appreciated role of organ boundaries in disease. Using Drosophila as a model, we here show that a specific population of adult midgut...

..., Belgium 07 09 200 18 07 2000 © 2000 by Company of Biologists 2000 Ecdysone biosynthesis P450 Epidermis Midgut Drosophila melanogaster The steroid hormone 20-hydroxyecdysone (20E) coordinates many aspects of Drosophila development (reviewed by Riddiford, 1993...

... morphogenesis. Drosophila midgut development is regulated by homeotic genes expressed in the visceral mesoderm, where two of their target genes have been identified. Both encode secreted proteins. The Ultrabithorax ( Ubx ) homeotic gene activates transcription of the decapentaplegic ( dpp ) gene, which encodes...

...Rolf Reuter ABSTRACT The gut of Drosophila consists of ectodermally derived foregut and hindgut and endodermally derived midgut. Here I show that the gene serpent plays a key role in the development of the endoderm. serpent embryos lack the entire midgut and do not show endodermal differentiation...

...Ulrich Tepass; Volker Hartenstein ABSTRACT The reorganization of mesenchymal cells into an epithelial sheet is a widely used morphogenetic process in metazoans. An example of such a process is the formation of the Drosophila larval midgut epithelium that develops through a mesenchymal-epithelial...

...Rolf Reuter; Barbara Grunewald; Maria Leptin ABSTRACT The endodermal midgut arises from two primordia, the anterior midgut (AMG) primordium and the posterior midgut (PMG) primordium, which are separated by almost the entire length of the Drosophila embryo. To form the midgut, these two parts have...

... is tissuespecific and confined to the developing midgut endoderm and its precursors during embryogenesis. Tissue specificity of expression is maintained through later stages of development as β ν transcripts are found exclusively in the larval midgut. Within this structure, β ν transcripts are especially...

... is probably due to the anterior and posterior midgut primordia. In any event, it follows the appearance of ecdysone receptor mRNA ( Koelle et al., 1991 ) and occurs at about the time of a well-established ecdysone peak ( Richards, 1981 ). Similarly, expression in the epidermis and fat body during L1 and L2...