... to fertilization. RGS2 G q Oocyte Meiotic maturation Calcium Egg activation Fully grown mammalian oocytes are arrested in meiotic prophase until a mid-cycle release of luteinizing hormone from the pituitary stimulates resumption of meiosis to the metaphase II (MII) stage, referred to herein...

... to this work † Author for correspondence (e-mail: [email protected] ) 22 4 2009 © 2009. 2009 MSP signaling Notch signaling Meiosis Meiotic maturation Germline stem cell Cytoplasmic streaming Caenorhabditis elegans A key question in developmental biology is how...

... evolutionary conservation are incompletely understood. In C. elegans , a sperm-sensing mechanism regulates oocyte meiotic maturation and ovulation, tightly coordinating sperm availability and fertilization. Sperm release the major sperm protein (MSP)signal to trigger meiotic resumption (meiotic maturation...

.... McCarter, J., Bartlett, B., Dang, T. and Schedl, T. ( 1999 ). On the control of oocyte meiotic maturation and ovulation in Caenorhabditis elegans . Dev. Biol. 205 , 111 -28. McDowall, J. S. and Rose, A. M. ( 1997 ). Genetic analysis of sterile mutants in the dpy-5 unc-13 (I) genomic region...

... for both oocyte meiotic maturation and ovarian muscle contraction. The identification of the signaling function of MSP raised the question, how do spermatozoa, which are devoid of ribosomes, ER and Golgi, release a cytoplasmic protein lacking a signal sequence? Here, we provide evidence that MSP export...

... stimulation of immature oocytes results in a change in the distribution of XaPKC 2-3 hours after the completion of germinal vesicle breakdown, which requires the kinase activity of aPKC. These results suggest that meiotic maturation induces the animal-vegetal asymmetry of aPKC. * Author...

...John Carroll; Karl Swann; David Whittingham; Michael Whitaker ABSTRACT Calcium oscillations occur during meiotic maturation of mouse oocytes. They also trigger activation at fertilization. We have monitored [Ca 2+ ] i in oocytes at different stages of growth and maturation to examine how...

...Catherine Jessus; Héléne Rime; Olivier Haccard; Johan Van Lint; Jozef Goris; Wilfried Merlevede; RenÉ Ozon ABSTRACT The tyrosine phosphorylation/dephosphorylation of p34 cdc2 was estimated by immunoblotting with antiphosphotyrosine antibody during meiotic maturation of Xenopus oocytes. At the time...

.... * Author for correspondence (e-mail: [email protected] ) 21 02 1997 © 1990 by Company of Biologists 1990 cortical granule oocyte fertilization meiotic maturation Lytechinus variegatus Cortical granule exocytosis is a conserved mechanism in the block to polyspermy...

.... This suggests that the mechanism responsible for the developmental arrest of mature oocytes at metaphase II depends on cytoplasmic conditions that cause chromosome condensation to the metaphase state. 24 05 1988 © 1988 by Company of Biologists 1988 mouse oocyte meiotic maturation...

...-promoting factor MPF starfish oocytes meiotic maturation embryogenesis microinjection In the animal kingdom, oocytes enter meiosis, which is then arrested for a long period of time (from several weeks to several years) at the first meiotic prophase. At the end of vitellogenesis, the fully grown...