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Keywords: mRNA localisation
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Journal Articles
Journal: Development
Development (2004) 131 (23): 5897–5907.
Published: 1 December 2004
... . To elucidate the molecular pathways triggered by Par-1, we have performed a genome-wide,high-throughput screen for Par-1 targets. Among the targets identified in this screen was Exuperantia (Exu), a mediator of bicoid mRNA localisation. We show that Exu is a phosphoprotein whose phosphorylation is dependent...
Journal Articles
Journal: Development
Development (2004) 131 (17): 4251–4261.
Published: 1 September 2004
... that localised pair-rule transcripts target their proteins in close proximity to the nuclei and increase the reliability of the segmentation process by augmenting gene activity. Our data suggest that mRNA localisation signals in pair-rule transcripts affect nuclear protein uptake and thereby adjust gene activity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (5): 665–673.
Published: 1 March 2001
... back to the oocyte. We report that Drosophila Merlin is specifically required only within the posterior follicle cells to initiate axis formation. Merlin mutants show defects in nuclear migration and mRNA localisation in the oocyte. Merlin is not required to specify posterior follicle cell identity...