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Keywords: loxP
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Journal Articles

Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish

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Christian Mosimann, Charles K. Kaufman, Pulin Li, Emily K. Pugach, Owen J. Tamplin, Leonard I. Zon
Journal: Development
Development (2011) 138 (1): 169–177.
https://doi.org/10.1242/dev.059345
Published: 1 January 2011
... transplantation experiments to assess true multilineage potential of engrafted cells. We further generated transgenic zebrafish that express ubiquitous 4-hydroxytamoxifen-controlled Cre recombinase activity from a ubi:cre ERt2 transgene, as well as ubi:loxP-EGFP-loxP-mCherry (ubi:Switch) transgenics and show...
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Journal Articles

Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development

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Matthew M. Goddeeris, Robert Schwartz, John Klingensmith, Erik N. Meyers
Journal: Development
Development (2007) 134 (8): 1593–1604.
https://doi.org/10.1242/dev.02824
Published: 15 April 2007
... for correspondence (e-mail: [email protected]) 30 1 2007 © 2007. 2007 Anterior heart field (AHF) Neural crest Shh Outflow tract Congenital heart defect Hedgehog Cre loxP Septation Mouse The morphogenesis of the outflow tract (OFT) of the heart is a complex process...
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Includes: Supplementary data
Journal Articles

Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities

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Mattias Bjarnegård, Maria Enge, Jenny Norlin, Sigrun Gustafsdottir, Simon Fredriksson, Alexandra Abramsson, Minoru Takemoto, Erika Gustafsson, Reinhard Fässler, Christer Betsholtz
Journal: Development
Development (2004) 131 (8): 1847–1857.
https://doi.org/10.1242/dev.01080
Published: 15 April 2004
.... * Author for correspondence (e-mail: [email protected]) 17 12 2003 © 2004. 2004 PDGFB Endothelium Cre loxP Pericytes Microaneurysm In the process of vasculogenesis leading to the formation of primitive vascular plexuses and large vessels of vertebrate embryos...
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