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Keywords: limb development
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Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (5): dev200282.
Published: 11 March 2022
...Takashi Takeuchi; Haruka Matsubara; Fumina Minamitani; Yukio Satoh; Sayo Tozawa; Tomoki Moriyama; Kohei Maruyama; Ken-ichi T. Suzuki; Shuji Shigenobu; Takeshi Inoue; Koji Tamura; Kiyokazu Agata; Toshinori Hayashi ABSTRACT The 5′Hox genes play crucial roles in limb development and specify regions...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2020) 147 (19): dev180042.
Published: 5 October 2020
... chromatid segregation and promoting daughter cell intercalations that shape the early limb bud. Iroquois Cohesin Limb development Mesodermal cell intercalations Mitotic chromatid segregation Morphogenesis Iroquois (Irx) genes were first identified as regulators of pre-pattern that control...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (21): dev190967.
Published: 14 August 2020
... syndrome, and Lowry-Wood syndrome. Similarly, primordial dwarfism in domesticated animals is linked to positive selection in minor spliceosome components. Despite being vital for limb development and size regulation, its role remains unexplored. Here, we disrupt minor spliceosome function in the developing...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2018) 145 (7): dev161208.
Published: 29 March 2018
.... Published by The Company of Biologists Ltd 2018 http://www.biologists.com/user-licence-1-1/ Summary: Global profiling of five transcription factors associated with connective tissue subtypes reveals molecular signatures regulated during limb development and provides a data resource for future...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (3): dev160093.
Published: 8 February 2018
... abnormalities when overexpressed. Limk1 Axon guidance Clubfoot Limb development Chicken Congenital talipes equinovarus (CTEV, also known as ‘clubfoot’) is a human lower limb developmental defect with a worldwide prevalence of 1-3 cases for every 1000 live births, making it one of the most...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2017) 144 (13): 2480–2489.
Published: 1 July 2017
... truncation of anterior-proximal limb elements in mice. Hand1 bHLH Dimerization Limb development Transcription Mouse The vertebrate limb is an evolutionarily dynamic structure that has adapted broadly to fit the intended functional role, be it running, climbing, flying or swimming...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (3): 479–486.
Published: 1 February 2017
...Patricia Saiz-Lopez; Kavitha Chinnaiya; Matthew Towers; Maria A. Ros ABSTRACT An intrinsic timing mechanism specifies the positional values of the zeugopod (i.e. radius/ulna) and then autopod (i.e. wrist/digits) segments during limb development. Here, we have addressed whether this timing mechanism...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (24): 4608–4619.
Published: 15 December 2016
..., suggesting that similar mechanisms might regulate lineage-restricted progenitor cells during organogenesis. To gain insight into the effects of Prmt5 on limb development, we first examined its expression pattern in developing mouse embryos. At E11.5, Prmt5 is dynamically expressed, with high levels...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (19): 3491–3505.
Published: 1 October 2016
... by The Company of Biologists Ltd 2016 Summary: Inhibiting fibroblast migration during regeneration in axolotl reveals the importance of fibroblasts for blastema-based limb regeneration but not non-blastemal skin regrowth. Beryllium Regeneration Wound healing Limb development Ambystoma...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (16): 2994–3001.
Published: 15 August 2016
... of the mouse limb . Development   132 , 797 - 803 . 10.1242/dev.01613 Sun , M. , Ma , F. , Zeng , X. , Liu , Q. , Zhao , X.-L. , Wu , F.-X. , Wu , G.-P. , Zhang , Z.-F. , Gu , B. , Zhao , Y.-F. , et al. ( 2008 ). Triphalangeal thumb-polysyndactyly syndrome...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (4): 672–680.
Published: 15 February 2015
...Idit Eshkar-Oren; Sharon Krief; Napoleone Ferrara; Alison M. Elliott; Elazar Zelzer Blood vessels serve as key regulators of organogenesis by providing oxygen, nutrients and molecular signals. During limb development, programmed cell death (PCD) contributes to separation of the digits...
Journal Articles
Journal: Development
Development (2014) 141 (9): 1906–1914.
Published: 1 May 2014
... number in the vertebrate limb . Development 136 , 3515 - 3524 . 10.1242/dev.037507 Capdevila J. , Tsukui T. , Rodríquez Esteban C. , Zappavigna V. , Izpisúa Belmonte J. C. ( 1999 ). Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (8): 1715–1725.
Published: 15 April 2014
... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Sonic hedgehog Long-range regulation ZRS Limb development Mouse The regulatory activity that directs limb-specific expression of Shh is contained within a 1.7-kb Hin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4574–4582.
Published: 15 November 2013
.... Cell 8 , 677 – 688 . Izpisúa-Belmonte J. C. , Duboule D. ( 1992 ). Homeobox genes and pattern formation in the vertebrate limb . Dev. Biol. 152 , 26 – 36 . Kardon G. ( 1998 ). Muscle and tendon morphogenesis in the avian hind limb . Development 125 , 4019...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (10): 2130–2138.
Published: 15 May 2013
...Rushikesh Sheth; Damien Grégoire; Annie Dumouchel; Martina Scotti; Jessica My Trang Pham; Stephen Nemec; Maria Félix Bastida; Marian A. Ros; Marie Kmita Limb development relies on an exquisite coordination between growth and patterning, but the underlying mechanisms remain elusive. Anterior...
Includes: Supplementary data