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1-20 of 150
Keywords: limb development
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Journal Articles
In collection:
Musculoskeletal system
Yanshu Wang, Arjun Venkatesh, Jiajia Xu, Mingxin Xu, John Williams, Philip M. Smallwood, Aaron James, Jeremy Nathans
Journal:
Development
Development (2022) 149 (9): dev200340.
Published: 12 May 2022
.... WNT7A and RECK have been shown previously to play a role in limb development, but the mechanism of RECK action in this context is unknown. The roles of WNT7B and GPR124 in limb development have not been investigated. Using combinations of conventional and/or conditional loss-of-function alleles...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Takashi Takeuchi, Haruka Matsubara, Fumina Minamitani, Yukio Satoh, Sayo Tozawa, Tomoki Moriyama, Kohei Maruyama, Ken-ichi T. Suzuki, Shuji Shigenobu, Takeshi Inoue, Koji Tamura, Kiyokazu Agata, Toshinori Hayashi
Journal:
Development
Development (2022) 149 (5): dev200282.
Published: 11 March 2022
...Takashi Takeuchi; Haruka Matsubara; Fumina Minamitani; Yukio Satoh; Sayo Tozawa; Tomoki Moriyama; Kohei Maruyama; Ken-ichi T. Suzuki; Shuji Shigenobu; Takeshi Inoue; Koji Tamura; Kiyokazu Agata; Toshinori Hayashi ABSTRACT The 5′Hox genes play crucial roles in limb development and specify regions...
Includes: Supplementary data
Journal Articles
Julie Gamart, Iros Barozzi, Frédéric Laurent, Robert Reinhardt, Laurène Ramos Martins, Thomas Oberholzer, Axel Visel, Rolf Zeller, Aimée Zuniga
Journal:
Development
Development (2021) 148 (23): dev200182.
Published: 3 December 2021
... and dorsal-ventral patterning of the limb . Development 128 , 4449 - 4461 . 10.1242/dev.128.22.4449 Anders , S. , Pyl , P. T. and Huber , W. ( 2015 ). HTSeq--a Python framework to work with high-throughput sequencing data . Bioinformatics 31 , 166 - 169 . 10.1093...
Includes: Supplementary data
Journal Articles
Hirotaka Tao, Jean-Philippe Lambert, Theodora M. Yung, Min Zhu, Noah A. Hahn, Danyi Li, Kimberly Lau, Kendra Sturgeon, Vijitha Puviindran, Xiaoyun Zhang, Wuming Gong, Xiao Xiao Chen, Gregory Anderson, Daniel J. Garry, R. Mark Henkelman, Yu Sun, Angelo Iulianella, Yasuhiko Kawakami, Anne-Claude Gingras, Chi-chung Hui, Sevan Hopyan
Journal:
Development
Development (2020) 147 (19): dev180042.
Published: 5 October 2020
... chromatid segregation and promoting daughter cell intercalations that shape the early limb bud. Iroquois Cohesin Limb development Mesodermal cell intercalations Mitotic chromatid segregation Morphogenesis Iroquois (Irx) genes were first identified as regulators of pre-pattern that control...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2020) 147 (21): dev190967.
Published: 14 August 2020
... syndrome, and Lowry-Wood syndrome. Similarly, primordial dwarfism in domesticated animals is linked to positive selection in minor spliceosome components. Despite being vital for limb development and size regulation, its role remains unexplored. Here, we disrupt minor spliceosome function in the developing...
Includes: Supplementary data
Journal Articles
Richard Sarro, Acadia A. Kocher, Deena Emera, Severin Uebbing, Emily V. Dutrow, Scott D. Weatherbee, Timothy Nottoli, James P. Noonan
Journal:
Development
Development (2018) 145 (7): dev158550.
Published: 9 April 2018
... of Health 10.13039/100000002 F32 GM106628 T32 GM007223 T32 HD007149 National Institute of General Medical Sciences 10.13039/100000057 GM094780 Enhancer-promoter interactions Genomics Limb development Enhancer loss-of-function mutations Summary: Long-range regulatory...
Includes: Supplementary data
Journal Articles
In collection:
Musculoskeletal system
Mickael Orgeur, Marvin Martens, Georgeta Leonte, Sonya Nassari, Marie-Ange Bonnin, Stefan T. Börno, Bernd Timmermann, Jochen Hecht, Delphine Duprez, Sigmar Stricker
Journal:
Development
Development (2018) 145 (7): dev161208.
Published: 29 March 2018
.... Published by The Company of Biologists Ltd 2018 http://www.biologists.com/user-licence-1-1/ Summary: Global profiling of five transcription factors associated with connective tissue subtypes reveals molecular signatures regulated during limb development and provides a data resource for future...
Includes: Supplementary data
Journal Articles
J. Martin Collinson, Nils O. Lindström, Carlos Neves, Karen Wallace, Caroline Meharg, Rebecca H. Charles, Zoe K. Ross, Amy M. Fraser, Ivan Mbogo, Kadri Oras, Masaru Nakamoto, Simon Barker, Suzanne Duce, Zosia Miedzybrodzka, Neil Vargesson
Journal:
Development
Development (2018) 145 (3): dev160093.
Published: 8 February 2018
... abnormalities when overexpressed. Limk1 Axon guidance Clubfoot Limb development Chicken Congenital talipes equinovarus (CTEV, also known as ‘clubfoot’) is a human lower limb developmental defect with a worldwide prevalence of 1-3 cases for every 1000 live births, making it one of the most...
Includes: Supplementary data
Journal Articles
Michiko Yamashita, Kazuki Inoue, Noritaka Saeki, Maky Ideta-Otsuka, Yuta Yanagihara, Yuichiro Sawada, Iori Sakakibara, Jiwon Lee, Koichi Ichikawa, Yoshiaki Kamei, Tadahiro Iimura, Katsuhide Igarashi, Yasutsugu Takada, Yuuki Imai
Journal:
Development
Development (2018) 145 (1): dev157412.
Published: 8 January 2018
... for progression of some cancers. However, the functional role of Uhrf1 in other processes, such as limb development, is unknown. In this study, we generated limb mesenchymal cell-specific Uhrf1 knockout mice ( Uhrf1 Δ Limb/ Δ Limb , cKO). The cKO mice had short and deformed limbs caused by growth plate...
Includes: Supplementary data
Journal Articles
Beth A. Firulli, Hannah Milliar, Kevin P. Toolan, Jade Harkin, Robyn K. Fuchs, Alex G. Robling, Anthony B. Firulli
Journal:
Development
Development (2017) 144 (13): 2480–2489.
Published: 1 July 2017
... truncation of anterior-proximal limb elements in mice. Hand1 bHLH Dimerization Limb development Transcription Mouse The vertebrate limb is an evolutionarily dynamic structure that has adapted broadly to fit the intended functional role, be it running, climbing, flying or swimming...
Includes: Supplementary data
Journal Articles
In collection:
Musculoskeletal system
Journal:
Development
Development (2017) 144 (3): 479–486.
Published: 1 February 2017
...Patricia Saiz-Lopez; Kavitha Chinnaiya; Matthew Towers; Maria A. Ros ABSTRACT An intrinsic timing mechanism specifies the positional values of the zeugopod (i.e. radius/ulna) and then autopod (i.e. wrist/digits) segments during limb development. Here, we have addressed whether this timing mechanism...
Includes: Supplementary data
Journal Articles
Jacqueline L. Norrie, Qiang Li, Swanie Co, Bau-Lin Huang, Ding Ding, Jann C. Uy, Zhicheng Ji, Susan Mackem, Mark T. Bedford, Antonella Galli, Hongkai Ji, Steven A. Vokes
Journal:
Development
Development (2016) 143 (24): 4608–4619.
Published: 15 December 2016
..., suggesting that similar mechanisms might regulate lineage-restricted progenitor cells during organogenesis. To gain insight into the effects of Prmt5 on limb development, we first examined its expression pattern in developing mouse embryos. At E11.5, Prmt5 is dynamically expressed, with high levels...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Journal:
Development
Development (2016) 143 (19): 3491–3505.
Published: 1 October 2016
... by The Company of Biologists Ltd 2016 Summary: Inhibiting fibroblast migration during regeneration in axolotl reveals the importance of fibroblasts for blastema-based limb regeneration but not non-blastemal skin regrowth. Beryllium Regeneration Wound healing Limb development Ambystoma...
Includes: Supplementary data
Journal Articles
In collection:
Chromatin and epigenetics
Journal:
Development
Development (2016) 143 (16): 2994–3001.
Published: 15 August 2016
... of the mouse limb . Development 132 , 797 - 803 . 10.1242/dev.01613 Sun , M. , Ma , F. , Zeng , X. , Liu , Q. , Zhao , X.-L. , Wu , F.-X. , Wu , G.-P. , Zhang , Z.-F. , Gu , B. , Zhao , Y.-F. , et al. ( 2008 ). Triphalangeal thumb-polysyndactyly syndrome...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2015) 142 (9): 1672–1683.
Published: 1 May 2015
.... Limb development is a well-studied topic in vertebrate organogenesis. Nevertheless, there is still little understanding of tissue-level deformation relative to molecular and cellular dynamics. This is mainly because live recording of detailed cell behaviors in whole tissues is technically difficult...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2015) 142 (4): 672–680.
Published: 15 February 2015
...Idit Eshkar-Oren; Sharon Krief; Napoleone Ferrara; Alison M. Elliott; Elazar Zelzer Blood vessels serve as key regulators of organogenesis by providing oxygen, nutrients and molecular signals. During limb development, programmed cell death (PCD) contributes to separation of the digits...
Journal Articles
Qiang Li, Jordan P. Lewandowski, Marian B. Powell, Jacqueline L. Norrie, Seung Hee Cho, Steven A. Vokes
Journal:
Development
Development (2014) 141 (9): 1906–1914.
Published: 1 May 2014
... number in the vertebrate limb . Development 136 , 3515 - 3524 . 10.1242/dev.037507 Capdevila J. , Tsukui T. , Rodríquez Esteban C. , Zappavigna V. , Izpisúa Belmonte J. C. ( 1999 ). Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2014) 141 (8): 1715–1725.
Published: 15 April 2014
... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Sonic hedgehog Long-range regulation ZRS Limb development Mouse The regulatory activity that directs limb-specific expression of Shh is contained within a 1.7-kb Hin...
Includes: Supplementary data
Journal Articles
Ilea T. Swinehart, Aleesa J. Schlientz, Christopher A. Quintanilla, Douglas P. Mortlock, Deneen M. Wellik
Journal:
Development
Development (2013) 140 (22): 4574–4582.
Published: 15 November 2013
.... Cell 8 , 677 – 688 . Izpisúa-Belmonte J. C. , Duboule D. ( 1992 ). Homeobox genes and pattern formation in the vertebrate limb . Dev. Biol. 152 , 26 – 36 . Kardon G. ( 1998 ). Muscle and tendon morphogenesis in the avian hind limb . Development 125 , 4019...
Includes: Supplementary data
Journal Articles
Rushikesh Sheth, Damien Grégoire, Annie Dumouchel, Martina Scotti, Jessica My Trang Pham, Stephen Nemec, Maria Félix Bastida, Marian A. Ros, Marie Kmita
Journal:
Development
Development (2013) 140 (10): 2130–2138.
Published: 15 May 2013
...Rushikesh Sheth; Damien Grégoire; Annie Dumouchel; Martina Scotti; Jessica My Trang Pham; Stephen Nemec; Maria Félix Bastida; Marian A. Ros; Marie Kmita Limb development relies on an exquisite coordination between growth and patterning, but the underlying mechanisms remain elusive. Anterior...
Includes: Supplementary data
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