Skip Nav Destination
Close Modal
Update search
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
NARROW
Date
Availability
1-20 of 32
Keywords: limb bud
Close
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
1
Sort by
Journal Articles
Geoffrey Soussi, Ausra Girdziusaite, Shalu Jhanwar, Victorio Palacio, Marco Notaro, Rushikesh Sheth, Rolf Zeller, Aimée Zuniga
Journal:
Development
Development (2024) 151 (11): dev202722.
Published: 3 June 2024
...Geoffrey Soussi; Ausra Girdziusaite; Shalu Jhanwar; Victorio Palacio; Marco Notaro; Rushikesh Sheth; Rolf Zeller; Aimée Zuniga ABSTRACT During limb bud formation, axis polarities are established as evidenced by the spatially restricted expression of key regulator genes. In particular, the mutually...
Includes: Supplementary data
Journal Articles
Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds
Available to Purchase
Journal:
Development
Development (2012) 139 (22): 4250–4260.
Published: 15 November 2012
...Jean-Denis Bénazet; Emanuele Pignatti; Ashleigh Nugent; Erkan Unal; Frédéric Laurent; Rolf Zeller SMAD4 is an essential mediator of canonical TGFβ/BMP signal transduction and we inactivated Smad4 in mouse limb buds from early stages onward to study its functions in the mesenchyme. While this Smad4...
Includes: Multimedia, Supplementary data
Journal Articles
Ezh2 regulates anteroposterior axis specification and proximodistal axis elongation in the developing limb
Available to Purchase
Journal:
Development
Development (2011) 138 (17): 3759–3767.
Published: 1 September 2011
...Laurie A. Wyngaarden; Paul Delgado-Olguin; I-hsin Su; Benoit G. Bruneau; Sevan Hopyan Specification and determination (commitment) of positional identities precedes overt pattern formation during development. In the limb bud, it is clear that the anteroposterior axis is specified at a very early...
Journal Articles
Oriented cell motility and division underlie early limb bud morphogenesis
Available to PurchaseLaurie A. Wyngaarden, Kevin M. Vogeli, Brian G. Ciruna, Mathew Wells, Anna-Katerina Hadjantonakis, Sevan Hopyan
Journal:
Development
Development (2010) 137 (15): 2551–2558.
Published: 1 August 2010
...Laurie A. Wyngaarden; Kevin M. Vogeli; Brian G. Ciruna; Mathew Wells; Anna-Katerina Hadjantonakis; Sevan Hopyan The vertebrate limb bud arises from lateral plate mesoderm and its overlying ectoderm. Despite progress regarding the genetic requirements for limb development, morphogenetic mechanisms...
Includes: Multimedia, Supplementary data
Journal Articles
Specification of cell fate along the proximal-distal axis in the developing chick limb bud
Available to Purchase
Journal:
Development
Development (2007) 134 (7): 1397–1406.
Published: 1 April 2007
...Kosei Sato; Yutaka Koizumi; Masanori Takahashi; Atsushi Kuroiwa; Koji Tamura Pattern formation along the proximal-distal (PD) axis in the developing limb bud serves as a good model for learning how cell fate and regionalization of domains, which are essential processes in morphogenesis during...
Includes: Supplementary data
Journal Articles
Nuclear reorganisation and chromatin decondensation are conserved, but distinct, mechanisms linked to Hox gene activation
Available to Purchase
Journal:
Development
Development (2007) 134 (5): 909–919.
Published: 1 March 2007
... in differentiating embryonic stem (ES) cells and in the tailbud of the embryo. However, looping out and decondensation are not simply two different manifestations of the same underlying change in chromatin structure. We show that, in the limb bud of the embryonic day 9.5 embryo,where Hoxd is also activated...
Journal Articles
Journal:
Development
Development (2005) 132 (10): 2489–2499.
Published: 15 May 2005
... differentiation of ventral and posterior structures. In the mouse, when Tsg and Bmp7 are mutated, the siren phenotype results from the fusion of the limb buds in the ventroposterior midline owing to a paucity of posterior ventral mesoderm. In Xenopus , knockdown of Tsg and Bmp7 results in an analogous...
Includes: Supplementary data
Journal Articles
Gremlin -mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis
Available to Purchase
Journal:
Development
Development (2004) 131 (14): 3401–3410.
Published: 15 July 2004
...Odyssé Michos; Lia Panman; Kristina Vintersten; Konstantin Beier; Rolf Zeller; Aimée Zuniga Epithelial-mesenchymal feedback signaling is the key to diverse organogenetic processes such as limb bud development and branching morphogenesis in kidney and lung rudiments. This study establishes...
Journal Articles
Specification and determination of limb identity: evidence for inhibitory regulation of Tbx gene expression
Available to Purchase
Journal:
Development
Development (2002) 129 (1): 211–220.
Published: 1 January 2002
... expression there. *Author for correspondence (e-mail: [email protected] ) 3 10 2001 © 2002. 2002 Tbx5 Tbx4 Limb bud Specification Determination Chick Morphogenesis during development is often prearranged by the influence of localized determinants, by cell-cell...
Journal Articles
Delta 1-activated Notch inhibits muscle differentiation without affecting Myf5 and Pax3 expression in chick limb myogenesis
Available to Purchase
Journal:
Development
Development (2000) 127 (23): 5213–5224.
Published: 1 December 2000
... that of MyoD . Moreover, Myf5 and Pax3 expression is correlated with myoblast proliferation, while MyoD is detected in post-mitotic myoblasts. These data indicate that Myf5 and MyoD are involved in different steps during chick limb bud myogenesis, Myf5 acting upstream of MyoD . The progression of myoblasts...
Journal Articles
Distinct signaling molecules control Hoxa-11 and Hoxa-13 expression in the muscle precursor and mesenchyme of the chick limb bud
Available to Purchase
Journal:
Development
Development (1999) 126 (12): 2771–2783.
Published: 15 June 1999
...-specific manner by interacting with the limb mesenchyme and the cartilage elements. The molecular mechanisms that provide positional cues to the muscle precursors are still unknown. We have shown that the expression patterns of Hoxa-11 and Hoxa-13 are correlated with muscle patterning of the limb bud...
Journal Articles
Gli3 ( Xt ) and formin ( ld ) participate in the positioning of the polarising region and control of posterior limb-bud identity
Available to Purchase
Journal:
Development
Development (1999) 126 (1): 13–21.
Published: 1 January 1999
...Aimée Zúñiga; Rolf Zeller During initiation of limb-bud outgrowth in vertebrate embryos, the polarising region (limb-bud organizer) is established upon activation of the Sonic Hedgehog (SHH) signaling molecule at the posterior limb-bud margin. Another hallmark of establishing anteroposterior limb...
Journal Articles
Mutations in mouse Aristaless-like4 cause Strong’s luxoid polydactyly
Available to PurchaseShimian Qu, S. Craig Tucker, Jason S. Ehrlich, John M. Levorse, Lorraine A. Flaherty, Ron Wisdom, Thomas F. Vogt
Journal:
Development
Development (1998) 125 (14): 2711–2721.
Published: 15 July 1998
... on several interacting signaling centers; one of these, the zone of polarizing activity (ZPA), comprises a group of mesenchymal cells along the posterior aspect of the limb bud that express sonic hedgehog ( Shh ) and plays a key role in patterning the anterior-posterior (AP) axis. The mechanisms by which...
Journal Articles
Coordinated expression of Hoxa-11 and Hoxa-13 during limb muscle patterning
Available to PurchaseMasakazu Yamamoto, Yoshihiro Gotoh, Koji Tamura, Mikiko Tanaka, Atsushi Kawakami, Hiroyuki Ide, Atsushi Kuroiwa
Journal:
Development
Development (1998) 125 (7): 1325–1335.
Published: 1 April 1998
...Masakazu Yamamoto; Yoshihiro Gotoh; Koji Tamura; Mikiko Tanaka; Atsushi Kawakami; Hiroyuki Ide; Atsushi Kuroiwa ABSTRACT The limb muscle precursor cells migrate from the somites and congregate into the dorsal and ventral muscle masses in the limb bud. Complex muscle patterns are formed...
Journal Articles
Sonic hedgehog is not required for polarising activity in the Doublefoot mutant mouse limb bud
Available to Purchase
Journal:
Development
Development (1998) 125 (3): 351–357.
Published: 1 February 1998
... activity. The results reveal a gain-of-function mutation at a locus that mediates pattern formation in the developing limb. Shh expression is identical with that of wild-type embryos, i.e. there is no ectopic expression. However, mesenchyme from the anterior aspects of Dbf/+ mutant limb buds, when...
Journal Articles
Sonic Hedgehog induces proliferation of committed skeletal muscle cells in the chick limb
Available to Purchase
Journal:
Development
Development (1998) 125 (3): 495–505.
Published: 1 February 1998
.... Myogenic cells in limb skeletal muscles originate from the lateral half of the somites. Cells that migrate away from the lateral part of the somites to the limb bud do not initially express any member of the MRF family. Expression of MRFs in the muscle precursor cells starts after the migration process...
Journal Articles
Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants
Available to Purchase
Journal:
Development
Development (1997) 124 (24): 5021–5032.
Published: 15 December 1997
...-mail: [email protected] ) 3 10 1997 © 1997 by Company of Biologists 1997 mouse limb bud dorsoventral pattern Wnt-signaling apical ectodermal ridge Embryos from Wnt-7a +/ − ; En-1 +/ − intercrosses were collected at noon on the day of dissection. Each embryo...
Journal Articles
The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure
Available to Purchase
Journal:
Development
Development (1997) 124 (8): 1453–1463.
Published: 15 April 1997
... on an earlier stage (HH13). Using the quail-chick chimera system, we first show that the presumptive wing mesoderm occupies the medial half of the somatopleure at the level of somites 15-20. The corresponding ectodermal area, however, will only give rise to the apical ectodermal ridge. The rest of the limb bud...
Journal Articles
BMP-2/-4 mediate programmed cell death in chicken limb buds
Available to PurchaseYuji Yokouchi, Jyun-ichi Sakiyama, Takashi Kameda, Hideo Iba, Atsushi Suzuki, Naoto Ueno, Atsushi Kuroiwa
Journal:
Development
Development (1996) 122 (12): 3725–3734.
Published: 1 December 1996
...Yuji Yokouchi; Jyun-ichi Sakiyama; Takashi Kameda; Hideo Iba; Atsushi Suzuki; Naoto Ueno; Atsushi Kuroiwa ABSTRACT During limb development, the mesenchymal cells in restricted areas of limb bud, anterior necrotic zone, posterior necrotic zone, opaque zone and interdigital necrotic zones...
Journal Articles
Role of TGFβs and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod
Available to Purchase
Journal:
Development
Development (1996) 122 (8): 2349–2357.
Published: 1 August 1996
.... M. are both first authors 19 5 1996 © 1996 by Company of Biologists 1996 TGFβ apoptosis growth factor Msx-1 Msx-2 ck-erg BMP-4 cell death chick limb bud autopod The developing limb bud is a relatively simple structure consisting of mesoderm covered...
1