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Keywords: left-right asymmetry
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Journal: Development
Development (2021) 148 (17): dev199265.
Published: 6 September 2021
.... W. , Essner , J. J. and Yost , H. J. ( 2000 ). Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry . Development 127 , 3567 - 3579 . 10.1242/dev.127.16.3567 Bolger , A. M. , Lohse , M. and Usadel , B. ( 2014...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (19): dev187583.
Published: 12 October 2020
... by The Company of Biologists Ltd 2020 Summary: This Review aims to shed new light on the development of laterality in the stomach and intestine, challenging classical models of left-right asymmetric gut morphogenesis. Gut tube Intestine Laterality Left-right asymmetry Morphogenesis Stomach...
Journal Articles
Journal: Development
Development (2020) 147 (1): dev182469.
Published: 13 January 2020
... are the two key regulators for the establishment of amphioxus left-right asymmetry, likely representing an evolutionarily conserved mechanism in deuterostomes. Amphioxus Left-right asymmetry Embryonic development Hh signalling Cilium Bilateral symmetry is a fundamental feature of many animal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (1): dev182469.
Published: 13 January 2020
... , J. E. and Scott , M. P. ( 2005 ). Communicating with Hedgehogs . Nat. Rev. Mol. Cell Biol.   6 , 306 - 317 . 10.1038/nrm1622 Hu , G. , Li , G. , Wang , H. and Wang , Y. ( 2017 ). Hedgehog participates in the establishment of left-right asymmetry during...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (12): dev180398.
Published: 14 June 2019
.... We also uncovered evidence for defects in left-right asymmetry within atrial cardiomyocyte populations. Furthermore, we were able to detail defects in cardiac outflow tract and valve development associated with Pitx2 . Our findings offer insight into Pitx2 function and provide a compilation of gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (12): dev180398.
Published: 14 June 2019
.... We also uncovered evidence for defects in left-right asymmetry within atrial cardiomyocyte populations. Furthermore, we were able to detail defects in cardiac outflow tract and valve development associated with Pitx2 . Our findings offer insight into Pitx2 function and provide a compilation of gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev173575.
Published: 10 May 2019
... induces and patterns the frog left-right organizer in the early gastrula and regulates the morphogenesis of the flow sensor following specification of the precursor tissue. FGF Pkd2 Sprouty Left-right asymmetry Leftward flow LRO Left-right (LR) asymmetry of inner organs is present...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (2014) 141 (8): 1603–1613.
Published: 15 April 2014
... License ( http://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Cilia Evolution Left-right asymmetry Left-right organizer Leftward flow Symmetry is a guiding...
Journal Articles
Journal: Development
Development (2013) 140 (22): 4465–4470.
Published: 15 November 2013
... summarize here, leaders in the field gathered at the symposium to discuss recent advances in understanding how left-right asymmetry is generated and utilized across the animal kingdom. * Authors for correspondence ( rburdine@princeton.edu ; tcaspar@emory.edu ) Competing interests The authors...
Journal Articles
Journal: Development
Development (2013) 140 (7): 1550–1559.
Published: 1 April 2013
... giant larvae 2 ( lgl2 ) is expressed prominently in ciliated organs. Lgl proteins are involved in establishing cell polarity and have been implicated in vesicle trafficking. Here, we identified a role for Lgl2 in development of ciliated epithelia in Kupffer’s vesicle, which directs left-right asymmetry...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (18): 3257–3262.
Published: 15 September 2012
... Cilia Left-right asymmetry The establishment of left-right (LR) asymmetry during early embryogenesis is crucial for the correct positioning and morphogenesis of internal organs. This process involves a number of intricately regulated developmental mechanisms, some of which appear...
Journal Articles