... Wing, Hodgkin Building, Guy's Campus, London SE1 1UL,UK. 3 5 2006 © 2006. 2006 Chick Quail Embryo Head mesoderm Skeletal muscles Eye muscles Lateral rectus Branchiomeric muscles Mandibular arch Jaw muscles Lbx1 Paraxis En2 Myf5 MyoR Fgf8 Bmp7...

...Benjamin L. Martin; Richard M. Harland We have examined lbx1 expression in early X. laevis tadpoles. In contrast to amniotes, lbx1 is expressed in all of the myoblasts that contribute to the body wall musculature, as well as in a group of cells that migrate into the head. Despite this different...

... limbless, Lbx1 and Meox2 mutants, respectively. We thank Ms Elaine Sherville for technical assistance and A. Tasmadjian for met d/d mutant embryo preparation. We also thank Professor Colin Wendell-Smith for sharing unpublished data and comments on manuscript. We appreciate the comments made by Dr...

... and differentiation of graft-derived cells were assayed using QCPN and QH1 antibodies to identify all quail cells and quail endothelial cells, respectively. Chimeric embryos were assayed for expression of myf5, myod, paraxis and lbx1 , and the synthesis of myosin heavy chain (MyHC), between 1 and 6 days later (stages...

...Roy C. Mootoosamy; Susanne Dietrich Most head muscles arise from the pre-otic axial and paraxial head mesoderm. This tissue does not form somites, yet expresses the somitic markers Lbx1 , Pax7 and Paraxis in a regionalised fashion. The domain set aside by these markers provides the lateral rectus...

... skeletal muscle. Previous studies have shown that Pax3, together with the c-Met receptor tyrosine kinase and its ligand Scatter Factor (SF) are necessary for the migration of hypaxial muscle precursors in mice. Lbx1 and Pax3 are co-expressed in all migrating hypaxial muscle precursors, raising...

...Henning Brohmann; Krzysztof Jagla; Carmen Birchmeier ABSTRACT The homeobox gene Lbx1 is expressed in migrating hypaxial muscle precursor cells during development. These precursors delaminate from the lateral edge of the dermomyotome and form distinct streams that migrate over large distances, using...

.... Migratory precursors are also correctly specified, as monitored by the expression of Lbx1 . However, these cells remain aggregated and fail to take up long range migration. We conclude that parallel but independent cues converge on the migratory hypaxial precursors in the dermomyotomal lip after...

... of this musculature, we cloned the chick Lbx1 gene that is specific to prospective hypaxial myoblasts at occipital, cervical and limb levels. Using this gene as a marker, we characterised the anatomical structures that produce the signals necessary for the specification of the hypaxial musculature by ablating them...