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Keywords: lag-2
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Journal Articles
Left-right asymmetry in C. elegans intestine organogenesis involves a LIN-12/Notch signaling pathway
Journal:
Development
Development (2000) 127 (16): 3429–3440.
Published: 15 August 2000
..., a receptor related to Notch; however, only cells in the left half of the primordium contact external, nonintestinal cells that express LAG-2, a ligand related to Delta. LIN-12 and LAG-2 mediated interactions result in the left primordial cells expressing lower levels of LIN-12 than the right primordial cells...
Journal Articles
Journal:
Development
Development (1995) 121 (12): 4275–4282.
Published: 1 December 1995
...Kevin Fitzgerald; Iva Greenwald ABSTRACT Ligands of the Delta/Serrate/lag-2 (DSL) family and their receptors, members of the lin-12/Notch family, mediate cell-cell interactions that specify cell fate in invertebrates and vertebrates. In C. elegans , two DSL genes, lag-2 and apx-1 , influence...
Journal Articles
Journal:
Development
Development (1994) 120 (10): 2913–2924.
Published: 1 October 1994
...Samuel T. Henderson; Dali Gao; Eric J. Lambie; Judith Kimble ABSTRACT The C. elegans lag-2 gene is required for several cell-cell interactions that rely on the receptors GLP-1 and LIN-12. In this paper, we report that lag-2 encodes a putative membrane protein with sequence similarity to Drosophila...