... periods than in control cells. In contrast, ammonia strongly inhibited accumulation of extracellular Camp without increasing the rate of extracellular cAMP hy drolysis, indicating that ammonia promotes accumu lation of intracellular cAMP by inhibiting cAMP se cretion. These results are consistent...

...-galactose epimerase, and at a later stage the exocytosis of preformed components of the spore coat. Evidence is presented here that this process is triggered by an elevated intracellular cAMP concentration. First, a number of rapidly developing ( rde ) mutants, whose cAMP metabolism had been investigated...