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Keywords: indian hedgehog
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Journal Articles
Journal: Development
Development (2017) 144 (7): 1165–1176.
Published: 1 April 2017
... output to a narrow distal regenerate zone comprising pObs and adjacent motile basal epidermal cells. This Hh/Smo activity is driven by epidermal Sonic hedgehog a (Shha) rather than Ob-derived Indian hedgehog a (Ihha), which nevertheless functions atypically to support bone maturation. Using BMS-833923...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (16): 2946–2957.
Published: 15 August 2016
....90.15.7230 Lozito , T. P. and Tuan , R. S. ( 2015 ). Lizard tail regeneration: regulation of two distinct cartilage regions by Indian hedgehog . Dev. Biol.   399 , 249 - 262 . 10.1016/j.ydbio.2014.12.036 Morrison , J. I. , Lööf , S. , He , P. P. and Simon...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (11): 1984–1991.
Published: 1 June 2015
... signaling stimulates the expression and activity of Indian hedgehog, increases the expression of β-catenin and inhibits Notch2. Our findings identify Vegfa as a regulator of perichondrial vascularity and osteoblast differentiation at early stages of bone development. In rescue experiments, Osx...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (1): 196–206.
Published: 1 January 2015
.... and O'Keefe , R. J. ( 2001 ). BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog . J. Orthop. Res. 19 , 18 - 25 . 10.1016/S0736-0266(00)00017-6 Hilton , M. J. , Tu , X. and Long , F. ( 2007 ). Tamoxifen-inducible gene deletion reveals...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3791–3801.
Published: 1 September 2011
...Shu-Hsuan C. Hsu; Xiaoyun Zhang; Chunying Yu; Zhu Juan Li; Jay S. Wunder; Chi-Chung Hui; Benjamin A. Alman Proper regulation of Indian hedgehog (Ihh) signaling is vital for chondrocyte proliferation and differentiation in the growth plate. Its dysregulation causes skeletal dysplasia, osteoarthritis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4667–4678.
Published: 1 December 2006
... by antagonistic BMP and FGF signaling pathways. © 2006. 2006 Bone morphogenetic protein Cartilage Chondrogenesis Fibroblast growth factor indian hedgehog BMP receptors Mouse Endochondral ossification is the multistep process that forms the majority of the skeletal system. This process...
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (2): 361–372.
Published: 15 January 2002
... from extra-embryonic mesodermal cells that underlie the visceral endoderm. Our previous studies have shown that Indian hedgehog ( Ihh ) is expressed in the visceral endoderm both in the visceral yolk sac in vivo and in embryonic stem (ES) cell-derived embryoid bodies. Differentiating embryoid bodies...
Journal Articles
Journal: Development
Development (2001) 128 (4): 541–550.
Published: 15 February 2001
... of wild-type cartilage during development, chondrocytes in A-CREB mutant cartilage exhibited a profound decrease in proliferative index and a delay in hypertrophy. Correspondingly, the expression of certain signaling molecules in cartilage, most notably the Indian hedgehog (Ihh) receptor patched (Ptch...
Journal Articles
Journal: Development
Development (2000) 127 (12): 2763–2772.
Published: 15 June 2000
... a critical role in coordinating patterning and organogenesis of the gut and its derivatives. We have assessed the function of Sonic hedgehog and Indian hedgehog genes, which encode members of the Hedgehog family of cell signals. Both are expressed in gut endoderm, whereas target genes are expressed...
Journal Articles
Journal Articles
Journal: Development
Development (1997) 124 (6): 1109–1117.
Published: 15 March 1997
... intense radial growth of the differentiating cartilages and disturb the formation of joints accompanied by alterations in the pattern of Indian hedgehog and ck-erg expression. Interestingly, the effects of these two BMPs on joint formation were found to be different. While the pre-dominant effect of BMP-2...
Journal Articles