... of a basic helix-loop-helix (bHLH) transcription factor gene, Hxt , that is expressed in early trophoblast and in differentiated giant cells. A separate gene, Hed , encodes a related protein that is expressed in maternal deciduum surrounding the implantation site. Overexpression of Hxt in mouse blastomeres...

... whereas it is suppressed by whereas extramacrochaete (emc) and hairy . All these genes encode helix-loop-helix proteins. The products of the achaete-scute complex and daughterless interact to form heterodimers able to activate transcription. In this report, we show that (1) extra-macrochaete forms...

...Andrew P. Jarman; Michael Brand; Lily Y. Jan; Yuh Nung Jan ABSTRACT asense is a member of the achaete-scute complex (AS-C) of helix-loop-helix genes involved in Drosophila neurogenesis. Unlike the other AS-C members, which are expressed in subsets of the ectodermal areas (proneural clusters...

...-of-scute of the achaete-scute complex. These genes encode basic helix-loop-helix proteins, which are nuclear transcription factors, as does the asense gene of the achaete-scute complex. Our studies suggest that asense is a neural precursor gene, rather than a proneural gene. Unlike the proneural achaete...