..., the phenotypic consequences of knocking-in well characterised human EGFR mutants can also be addressed. Homozygous hEGFR KI/KI mice are growth retarded but can survive for up to 6 months after birth. However, they display skin and hair growth defects similar to surviving Egfr -/- mice. Interestingly...

...Kenneth A. Horne; Colin A. B. Jahoda ABSTRACT The capacity of lower follicle dermal sheath to restore hair growth was tested by removing the lower halves of follicles, and then immediately implanting material containing dermal sheath cells from these bases, into the remaining upper epidermal...

...Colin A. B. Jahoda ABSTRACT Adult vibrissa follicle dermal papillae have the capacity to induce hair growth and follicle formation when associated with epidermis from various sources. However, the range of conditions under which hair follicle induction will take place has not been established...

...Amanda J. Reynolds; Colin A. B. Jahoda Adult rat pelage follicle dermal papilla cells induced follicle neogenesis and external hair growth when associated with adult footpad skin epidermis. They thus demonstrated a capacity to completely change the structural arrangement and gene expression...

... that received late passage cells (range 6 –15) produced hairs; and spontaneous regeneration of hair occurred in only 3 % of the control follicles. These results demonstrate that cultured papilla cells of early passage numbers retain their ability to induce hair growth. Histological examination confirmed...