...Aldo Ciau-Uitz; Philip Pinheiro; Arif Kirmizitas; Jie Zuo; Roger Patient The first haematopoietic stem cells share a common origin with the dorsal aorta and derive from putative adult haemangioblasts in the dorsal lateral plate (DLP) mesoderm. Here we show that the transcription factor (TF) stem...

...Guilherme Costa; Andrzej Mazan; Arnaud Gandillet; Stella Pearson; Georges Lacaud; Valerie Kouskoff At early stages of vertebrate ontogeny, blood and endothelial cells develop from a common mesodermal progenitor, the haemangioblast. Upon haematopoietic commitment, the haemangioblast generates blood...

... or proliferation, acts during gastrulation to drive cardiac fate and restrict anterior haemangioblast fate in zebrafish embryos. The haemangioblast programme was thought to be activated before the cardiac programme and is repressive towards it, suggesting that activation by Fgf of the cardiac programme might...

... to endothelial cells. However, the two populations give rise to distinct regions of the vasculature and are programmed differentially by BMP. † Author for correspondence (e-mail: [email protected]) 23 9 2002 ©2002. 2002 Blood Endothelium Haemangioblast BMP Transcription...

... of Wisconsin, 445 Henry Mall, Madison, WI 53706, USA 09 11 1987 © 1988 by Company of Biologists 1988 growth factor endothelium blood island haemangioblast vasculogenesis angiogenesis embryonic stem cell cystic embryoid body The vascular system originates from blood islands...