... the physical mechanisms underlying cell and tissue elongation and identifies some physical mechanisms of elongation that are conserved across species. Conserved mechanisms Elongation Growth Mechanics Mechanobiology Morphogenesis Alexander von Humboldt-Stiftung http://dx.doi.org/10.13039...

...Kota Banzai; Takashi Nishimura ABSTRACT Evolutionarily conserved insulin/insulin-like growth factor (IGF) signaling (IIS) correlates nutrient levels to metabolism and growth, thereby playing crucial roles in development and adult fitness. In the fruit fly Drosophila , ImpL2, an ortholog of IGFBP7...

... and reproduction in any medium provided that the original work is properly attributed. Summary: This Development at a Glance article describes how a cells’ limited repertoire of behaviours provide the basis for quantifying morphogenetic phenotypes. Cell behaviours Growth Morphogenesis Quantitative...

...Nathalie Bouré; Alexis Peaucelle; Magali Goussot; Bernard Adroher; Ludivine Soubigou-Taconnat; Néro Borrega; Eric Biot; Zakia Tariq; Marie-Laure Martin-Magniette; Véronique Pautot; Patrick Laufs; Nicolas Arnaud ABSTRACT Boundary domains delimit and organize organ growth throughout plant development...

... of p38 through Ser83, and that the phosphorylation of p38 during regeneration is nutrient sensitive. This mechanism is important for discriminating between p38 and JNK in the cells involved in tissue repair and regenerative growth. * Author for correspondence ( [email protected] ) Competing...

...Laura Boulan; Pierre Léopold ABSTRACT The sizes of living organisms span over 20 orders of magnitude or so. This daunting observation could intimidate researchers aiming to understand the general mechanisms controlling growth. However, recent progress suggests the existence of principles common...

...Caitlin McQueen; Matthew Towers ABSTRACT The vertebrate limb continues to serve as an influential model of growth, morphogenesis and pattern formation. With this Review, we aim to give an up-to-date picture of how a population of undifferentiated cells develops into the complex pattern of the limb...

... that controls cell number during planarian regeneration and nutrient-dependent growth/degrowth. Its expression depends on food ingestion and mTOR signaling. Body size Cell number Growth Regeneration Overgrowth mTOR Ministerio de Ciencia, Innovación y Universidades BFU2014-56055-P...

... that the SCFR correlates with glia differentiation of late retinal progenitor cells (RPCs), retinal vasculogenesis and homeostasis of the blood-retinal barrier. However, the role of SCF/SCFR signaling in the growth and development of the neural retina (NR), especially in the early embryonic stage, remains...

...John Robert Davis; Nicolas Tapon ABSTRACT The Hippo signalling pathway and its transcriptional co-activator targets Yorkie/YAP/TAZ first came to attention because of their role in tissue growth control. Over the past 15 years, it has become clear that, like other developmental pathways (e.g...

...Ainoa Planas-Riverola; Aditi Gupta; Isabel Betegón-Putze; Nadja Bosch; Marta Ibañes; Ana I. Caño-Delgado ABSTRACT Brassinosteroids (BRs) are steroid hormones that are essential for plant growth and development. These hormones control the division, elongation and differentiation of various cell...

...Kurt Buhler; Jason Clements; Mattias Winant; Lenz Bolckmans; Veerle Vulsteke; Patrick Callaerts ABSTRACT Growth and maturation are coordinated processes in all animals. Integration of internal cues, such as signalling pathways, with external cues, such as nutritional status, is paramount...

...Sarah D. Neuman; Arash Bashirullah ABSTRACT All animals must coordinate growth rate and timing of maturation to reach the appropriate final size. Here, we describe hobbit , a novel and conserved gene identified in a forward genetic screen for Drosophila animals with small body size. hobbit...

...H. Frederik Nijhout; Emily Laub; Laura W. Grunert ABSTRACT The wing imaginal disks of Lepidoptera can be grown in tissue culture, but require both insulin and ecdysone to grow normally. Here, we investigate the contributions the two hormones make to growth. Ecdysone is required to maintain mitoses...

..., in a mechanism reminiscent of ductal organ development and thyroid evolution from an exocrine forerunner. Thyroid Progenitor Fgf10 Sox9 Mouse Growth Differentiation Forskningsrådet om Hälsa, Arbetsliv och Välfärd; 2016-02360 Cancerfonden 10.13039/501100002794 14-0748 17...

...Kenneth D. Irvine; Boris I. Shraiman In his classic book On Growth and Form , D'Arcy Thompson discussed the necessity of a physical and mathematical approach to understanding the relationship between growth and form. The past century has seen extraordinary advances in our understanding...

... for the physical mechanisms of heart tube and foregut formation. According to our hypothesis, differential anisotropic growth between mesoderm and endoderm drives diagonal folding. Then, active contraction along the anterior intestinal portal generates tension to elongate the foregut and heart tube. We test...

... in the developing limbs and their function is required for limb growth in both insects and chordates. Despite the fundamental and conserved role that these transcription factors play during appendage development, their target genes and the mechanisms by which they participate in control limb growth are mostly...

...Idse Heemskerk; Thomas Lecuit; Loïc LeGoff In the course of morphogenesis, tissues change shape and grow. How this is orchestrated is largely unknown, partly owing to the lack of experimental methods to visualize and quantify growth. Here, we describe a novel experimental approach to investigate...

...Inna Averbukh; Danny Ben-Zvi; Siddhartha Mishra; Naama Barkai Morphogen gradients guide the patterning of tissues and organs during the development of multicellular organisms. In many cases, morphogen signaling is also required for tissue growth. The consequences of this interplay between growth...