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Keywords: grim
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Journal Articles
Journal: Development
Development (2004) 131 (24): 6093–6105.
Published: 15 December 2004
... in posterior segments prevents pioneer neuron death postmitotically and cell-autonomously by repressing the RHG-motif cell death activators reaper and grim . Our results identify the first clear case of a cell-autonomous and anti-apoptotic role for a Hox gene in vivo. In addition, they provide a novel...
Journal Articles
Journal: Development
Development (2004) 131 (10): 2409–2418.
Published: 15 May 2004
... involution defective,grim and reaper , which are required for ommatidial elimination. We estimate that approximately 6-8% of the total photoreceptor pool in each eye is removed by this mechanism. In addition, we show that the retinal apoptosis previously reported in apc1 mutants occurs at the same time...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (1): 123–133.
Published: 1 January 2003
... of the caspase inhibitor p35 or removal of the pro-apoptotic genes reaper, hid and grim ,showing that the glial cell undergoes apoptosis. Moreover, it seems that fragments are eliminated from the epithelium by mobile macrophages. Forcing survival of the glial cells induces precocious axonal outgrowth but does...
Journal Articles
Journal: Development
Development (1998) 125 (6): 1075–1082.
Published: 15 March 1998
... implicated in Drosophila apoptosis. The positive regulators, reaper (rpr), head involution defective (hid) and grim , as well as the negative regulators, DIAP1 and DIAP2 , are transcribed during oogenesis. However, germline clones homozygous for the deficiency Df(3)H99 , which deletes rpr, hid and grim...