... in posterior segments prevents pioneer neuron death postmitotically and cell-autonomously by repressing the RHG-motif cell death activators reaper and grim . Our results identify the first clear case of a cell-autonomous and anti-apoptotic role for a Hox gene in vivo. In addition, they provide a novel...

... involution defective,grim and reaper , which are required for ommatidial elimination. We estimate that approximately 6-8% of the total photoreceptor pool in each eye is removed by this mechanism. In addition, we show that the retinal apoptosis previously reported in apc1 mutants occurs at the same time...

... of the caspase inhibitor p35 or removal of the pro-apoptotic genes reaper, hid and grim ,showing that the glial cell undergoes apoptosis. Moreover, it seems that fragments are eliminated from the epithelium by mobile macrophages. Forcing survival of the glial cells induces precocious axonal outgrowth but does...

... implicated in Drosophila apoptosis. The positive regulators, reaper (rpr), head involution defective (hid) and grim , as well as the negative regulators, DIAP1 and DIAP2 , are transcribed during oogenesis. However, germline clones homozygous for the deficiency Df(3)H99 , which deletes rpr, hid and grim...