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Keywords: gene expression
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Journal Articles
Journal: Development
Development (2022) 149 (16): dev200398.
Published: 30 August 2022
...Laura J. Harrison; Daniel Bose ABSTRACT Enhancers confer precise spatiotemporal patterns of gene expression in response to developmental and environmental stimuli. Over the last decade, the transcription of enhancer RNAs (eRNAs) – nascent RNAs transcribed from active enhancers – has emerged...
Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (6): dev200491.
Published: 28 March 2022
... the low-sugar-induced increase in body size are not fully shared between the sexes, highlighting the importance of including males and females in larval studies even when similar phenotypic outcomes are observed. Fig. 4. A low-sugar diet has sex-biased effects on metabolic gene expression...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2021) 148 (13): dev199589.
Published: 6 July 2021
... cells rapidly diversify from each other, and investigation of the corresponding gene expression dynamics can help elucidate underlying cellular differentiation programs. However, current plant embryonic transcriptome datasets either lack cell-specific information or have RNA contamination from...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (11): dev199018.
Published: 12 June 2021
... and concomitantly undergo stronger downregulation by knockdown of either the intracellular Ca 2+ release channel IP 3 R or Set2. IP 3 /Ca 2+ signals thus regulate gene expression through Set2-mediated H3K36 marks on select neuronal genes for the larval to pupal transition. Datasets were evaluated for normality...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194019.
Published: 23 December 2020
...Ian J. Begeman; Kwangdeok Shin; Daniel Osorio-Méndez; Andrew Kurth; Nutishia Lee; Trevor J. Chamberlain; Francisco J. Pelegri; Junsu Kang ABSTRACT Heart regeneration in regeneration-competent organisms can be accomplished through the remodeling of gene expression in response to cardiac injury...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (15): dev186452.
Published: 14 August 2020
... by The Company of Biologists Ltd 2020 Summary: This Spotlight gives an overview of the discovery and current understanding of transcriptional adaptation, and discusses how its main features appear to be conserved across species. Transcriptional adaptation Gene expression Genetic compensation...
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (11): 1976–1987.
Published: 1 June 2017
... Notch signaling and coordinates a global transcriptional switch to promote placental vascular maturation. Its deficiency may underlie human placental disease. G9a Ehmt2 Vascular maturation Placental vascular development Intrauterine growth restriction Epigenetic regulators Gene expression...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (16): 2882–2897.
Published: 15 August 2016
...Swetansu K. Hota; Benoit G. Bruneau Precise gene expression ensures proper stem and progenitor cell differentiation, lineage commitment and organogenesis during mammalian development. ATP-dependent chromatin-remodeling complexes utilize the energy from ATP hydrolysis to reorganize chromatin...
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (3): 540–546.
Published: 1 February 2016
...L. Carine Stapel; Benoit Lombardot; Coleman Broaddus; Dagmar Kainmueller; Florian Jug; Eugene W. Myers; Nadine L. Vastenhouw Analysis of differential gene expression is crucial for the study of cell fate and behavior during embryonic development. However, automated methods for the sensitive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (18): 3073–3076.
Published: 15 September 2015
... and Newcastle, UK, was established to provide embryonic and fetal material for a variety of human studies ranging from single gene expression analysis to large-scale genomic/transcriptomic studies. Increasingly, HDBR material is enabling the derivation of stem cell lines and contributing towards developments...
Journal Articles
Journal: Development
Development (2015) 142 (8): 1418–1430.
Published: 15 April 2015
... gene expression during mesoderm induction. We find that Brg1 co-localizes with H3K27ac at distal enhancers and is required for robust H3K27 acetylation at distal enhancers that are activated during mesoderm induction. Brg1 is also required to maintain Polycomb-mediated repression of non-mesodermal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (21): 4158–4167.
Published: 1 November 2014
...Ahmet Ay; Jack Holland; Adriana Sperlea; Gnanapackiam Sheela Devakanmalai; Stephan Knierer; Sebastian Sangervasi; Angel Stevenson; Ertuğrul M. Özbudak The vertebrate segmentation clock is a gene expression oscillator controlling rhythmic segmentation of the vertebral column during embryonic...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2014) 141 (12): 2524–2532.
Published: 15 June 2014
... the atlas-builder software to benefit a large proportion of the developmental biology community, and the eNeuro atlas to serve as a publicly accessible hub for integrating neuronal attributes – cell lineage, gene expression patterns, axon/dendrite projections, neurotransmitters – and linking them...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (16): 3385–3394.
Published: 15 August 2013
.... Gene expression dynamics in early gut specification, as determined by single-molecule RNA FISH. ( A ) A portion of the gene network responsible for specifying the gut. ( B ) Images of fixed N2 (’wild type’) strain C. elegans embryos grown at 20°C. Scale bars: 10 μm. Left column: maximum merges...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (22): 4172–4179.
Published: 15 November 2012
... statement The authors declare no competing financial interests. 6 8 2012 © 2012. 2012 Cohesin Polycomb Gene expression Control of gene expression is vital to normal development. During Drosophila development, spatially and temporally restricted DNA-binding transcriptional...
Includes: Supplementary data