... and other tissues, and can diffuse into the pupal wing via the hemolymph. Cv-d binds to the BMPs Dpp and Gbb through its Vg domain, and to heparan sulfate proteoglycans, which are well-known for their role in BMP movement and accumulation in the wing. Cv-d acts over a long range in vivo, and does not have...

...Erdem Bangi; Kristi Wharton Wing patterning in Drosophila requires a Bmp activity gradient created by two Bmp ligands, Gbb and Dpp, and two Bmp type I receptors, Sax and Tkv. Gbb provides long-range signaling, while Dpp signals preferentially to cells near its source along the anteroposterior (AP...

...Robert P. Ray; Kristi A. Wharton The Drosophila BMP5/6/7/8 homolog, glass bottom boat ( gbb ), has been shown to be involved in proliferation and vein patterning in the wing disk. To better understand the roles for gbb in wing development, as well as its relationship with the Drosophila BMP2/4...

...Catharine A. Conley; Ross Silburn; Matthew A. Singer; Amy Ralston; Dan Rohwer-Nutter; David J. Olson; William Gelbart; Seth S. Blair ABSTRACT The BMP-like signaling mediated by the ligands Dpp and Gbb is required to reinforce the development of most veins in the Drosophila wing. However...