.... Here, we show that repression of Sgs expression is indirectly controlled by the BR-C through transcriptional down-regulation of fork head , a tissue-specific gene that plays a central role in salivary gland development and is required for Sgs expression. Our results demonstrate that integration...

... constriction. In embryos mutant for fork head (fkh), which encodes a transcription factor homologous to mammalian hepatocyte nuclear factor 3β (HNF-3β), the secretory primordia are not internalized and secretory tubes do not form. Here, we show that secretory cells of fkh mutant embryos undergo extensive...

...Kristy L. Kenyon; Sally A. Moody; Milan Jamrich Xlens1 is a novel Xenopus member of the fork head gene family, named for its nearly restricted expression in the anterior ectodermal placode, presumptive lens ectoderm (PLE), and anterior epithelium of the differentiated lens. The temporal and spatial...

... are achieved by the function of caudal in activating different target genes, namely folded gastrulation , which is required for invagination of the posterior gut primordium, and fork head and wingless , which are required to promote development of the internalized hindgut primordium. caudal is not sufficient...

... ; Matsuo et al., 1995 ; Acampora, 1995), Pax (reviewed by Chalepakis et al., 1993) and Wnt (McMahon and Bradley, 1990 ; Thomas and Capecchi, 1990) reveal their importance in the CNS. Recently, a new family of transcription factors containing the fork head domain has been identified...

... of parasegment 2, is among the earliest to be defined. It is soon divided into two distinct regions: the more dorsal pregland cells and the more ventral preduct cells. We show that it is the opposing activities of the Drosophila EGF receptor (DER) signaling pathway and the Fork head transcription factor...

... . 10.1083/jcb.109.5.2427 Jürgens , G. and Weigel , D. (1988). Terminal versus segmental development in the Drosophila embryo: The role of the homeotic gene fork head . Roux’s Arch. Dev. Biol . 197 , 345 – 354 . 10.1007/BF00375954 Jürgens , G. , Wieschaus , E...