..., parapineal neurons migrate unilaterally away from the rest of the pineal complex whereas rods, cones and projection neurons are non-migratory. The transcription factor Tbx2b is important for both the correct number and migration of parapineal neurons. We find that two additional transcription factors, Flh...

... effective than Shh and Twhh for primary motoneuron formation. Lateral views of islet1 + islet2 expression (both in blue) in wild-type embryo at 24 h (A); cyc;flh double mutant at 24 h (B); flh;syu double mutant at 18-19 h (C); and cyc;syu double mutant at 18-19 h (D). Scale bar: 50 μm. Fig. 4...

... of early mesodermal inducers (activin and ntl) and reveal an autoregulatory feedback loop between ntl and tbx-c . These data and analysis of midline (ntl − / − and flh − / −) and lateral mesoderm (spt − / −) mutants suggest that tbx-c may function during formation of the notochord. We describe...