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Keywords: fetal gonad
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Journal Articles

Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing mouse gonads

Megan L. Koth, S. Alexandra Garcia-Moreno, Annie Novak, Kirsten A. Holthusen, Anbarasi Kothandapani, Keer Jiang, Makoto Mark Taketo, Barbara Nicol, Humphrey H.-C. Yao, Christopher R. Futtner, Danielle M. Maatouk, Joan S. Jorgensen
Journal: Development
Development (2020) 147 (6): dev183814.
https://doi.org/10.1242/dev.183814
Published: 30 March 2020
.... © 2020. Published by The Company of Biologists Ltd 2020 http://www.biologists.com/user-licence-1-1/ Summary: Differential occupation of two enhancers defines sex-specific regulation of Irx3 and Irx5 in fetal gonads: repressor marks inhibit in testes, while active marks engage with β...
View articletitled, Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing mouse gonads
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Includes: Supplementary data
Journal Articles

Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells

Gerrit J. Bouma, Kenneth H. Albrecht, Linda L. Washburn, Andrew K. Recknagel, Gary A. Churchill, Eva M. Eicher
Journal: Development
Development (2005) 132 (13): 3045–3054.
https://doi.org/10.1242/dev.01890
Published: 1 July 2005
... the chromosome 4 gene Tda1 ; (3) B6 Dax1 -/Y fetal gonads initiate development as ovaries, even though Sry expression is activated at the correct time and at appropriate levels; (4) upregulation of Sox9 does not occur in B6 Dax1 -/Y fetal gonads in spite of apparently normal Sry expression; and (5...
View articletitled, Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells
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Includes: Supplementary data
Journal Articles

Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates adenylate cyclase and promotes proliferation of mouse primordial germ cells

Maurizio Pesce, Rita Canipari, Gian-Luca Ferri, Gregorio Siracusa, Massimo De Felici
Journal: Development
Development (1996) 122 (1): 215–221.
https://doi.org/10.1242/dev.122.1.215
Published: 1 January 1996
... that the mouse sex-determining gene Sry is expressed in the somatic cells of male fetal gonads and in the germ cell line in the adult testis . Mol. Reprod. Dev . 34 , 369 – 373 . Sethi , T. and Rozengurt , E. ( 1991a ). Multiple neuropeptide stimulate clonal growth of small cell lung...
View articletitled, Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates adenylate cyclase and promotes proliferation of mouse primordial germ cells
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