... and extraocular mesenchyme – are necessary for normal eye growth and differentiation. We have used explant cultures of chick optic vesicles to study the regulation of retinal pigmented epithelium (RPE) patterning and differentiation during early eye development. Our results show that extraocular mesenchyme...

... aspect of the embryo. To examine the potential role of non-mesodermal signals in specifying posterior (hematopoietic and endothelial) cell fates in the mouse embryo, we have devised a transgenic explant culture system. We show that interactions between primitive endoderm and adjacent embryonic ectoderm...

.... * Author for correspondence (e-mail: [email protected] ) 12 02 1998 01 04 1998 © 1998 by Company of Biologists 1998 Cranial neural crest Cell migration Chick Microinjection Fusion protein Whole mount immunostaining Explant culture Pattern formation Cell...

... of these cues have been hampered by the lack of an accessible assay system. To examine trunk neural crest migration over time and to perturb candidate guiding molecules, we have developed a novel explant preparation. Here, we demonstrate that trunk regions of the chicken embryo, placed in explant culture...

... transplantation explant culture References Adams , D. S. , Keller , R. and Koehl , M. A. R. ( 1990 ). The mechanics of notochord elongation, straightening and stiffening in the embryo of Xenopus laevis . Development 110 , 115 – 130 . Cardellini , P. ( 1988...

... and therefore the 2Al-protein is likely to be involved in processes essential for neurite extension, independent of the synaptic target. * Author for correspondence © 1990 by Company of Biologists 1990 axonal outgrowth cytoskeleton explant culture immune suppression monoclonal antibody...