...Aurélien Bidaud-Meynard; Ophélie Nicolle; Markus Heck; Yann Le Cunff; Grégoire Michaux ABSTRACT Intestine function relies on the strong polarity of intestinal epithelial cells and the array of microvilli forming a brush border at their luminal pole. Combining a genetic RNA interference (RNAi...

...Leonardo G. Guilgur; Pedro Prudêncio; Tânia Ferreira; Ana Rita Pimenta-Marques; Rui Gonçalo Martinho Epithelial cells mostly orient the spindle along the plane of the epithelium (planar orientation) for mitosis to produce two identical daughter cells. The correct orientation of the spindle relies...

... or not the cells were isolated or part of an epithelial cell island. Guidance by a multiple topographical cue is greater than could be predicted from cells’ reactions to a single cue (Clark et al. Development 99: 439-448, 1987). Substratum topography is considered to be an important cue in many developmental...

...M. H. Barcellos-Hoff; J. Aggeler; T. G. Ram; M. J. Bissell ABSTRACT An essential feature of mammary gland differentiation during pregnancy is the formation of alveoli composed of polarized epithelial cells, which, under the influence of lactogenic hormones, secrete vectorially and sequester milk...