... to the RID neuron and RID sister cell; the latter undergoes apoptosis shortly after cell division upon expression of the pro-apoptotic gene egl-1 . We observe UNC-3 expression in the RID progenitor, and the absence of UNC-3 results in the failure of the RID lineage to express a P egl-1 ::GFP reporter...

... on the cell-death activator EGL-1, a BH3-only protein required for programmed cell death in C. elegans , and can be prevented by a gain-of-function (gf) mutation in the cell-death specification gene ces-1 , which encodes a Snail-like DNA-binding protein. Here, we show that the genes hlh-2 and hlh-3 , which...