...Akanksha Bhatt; Valentin Ruffine; Uwe Töpfer; Jinhee Ryu; Elisabeth Fischer-Friedrich; Christian Dahmann ABSTRACT The elongation of tissues and organs is important for proper morphogenesis in animal development. In Drosophila ovaries, the elongation of egg chambers involves aligned Collagen IV...

... membrane play an important role in the proper elongation of the developing egg chamber; however, the molecular mechanisms contributing to basement membrane mechanical properties are not fully understood. Here, we systematically analyze the contributions of individual ECM components towards the molecular...

...Darcy Andersen; Sally Horne-Badovinac Organs are formed from multiple cell types that make distinct contributions to their shape. The Drosophila egg chamber provides a tractable model to dissect such contributions during morphogenesis. Egg chambers consist of 16 germ cells (GCs) surrounded...

... is determined by the expression of the pipe gene in a subpopulation of ventral follicle cells in the developing egg chamber. The Pipe protein exhibits homology to vertebrate glycosaminoglycan sulfotransferases. In a previous study, we demonstrated that embryonic DV polarity depends upon the sulfotransferase...

...-proteasome. These complexes are composed of three constant polypeptides – Skp1, Cullin1/3 and Roc1/Rbx1– and a fourth variable adapter, the F-box protein. Slimb (Slmb) is a Drosophila F-Box protein that fulfills several roles in development and cell physiology. We analyzed its participation in egg chamber...

... for correspondence (e-mail: [email protected] ) * These authors contributed equally to this work 20 10 2003 © 2004. 2004 Myc dmyc Proto-oncogene Nurse cells Follicle Egg chamber Gene amplification Dacapo Cyclin E Polyploidization Endoreduplication Since...

.... In this process, dome controls the expression of the apical determinant Crumbs. In contrast to the ligand Upd, whose expression is limited to a pair of polar cells at both ends of the egg chamber, dome is expressed in all germline and follicle cells. However, the Dome protein is specifically localized...

... in positioning Notch activation during early oogenesis, and establish a function for the polar cells in separating germline cysts into individual follicles. 5 4 2001 © 2001. 2001 fringe Notch Polar cells Oogenesis Follicle cells Egg chamber Drosophila Oogenesis...

... to the developing oocyte. Analysis of Src64 egg chambers showed defects in the ring canals that interconnect the oocyte and its 15 associated nurse cells. Src64 ring canals fail to accumulate the high levels of tyrosine phosphorylation that are normally present. Despite the reduced tyrosine phosphorylation, known...

... chorionic structures, the dorsal appendages ( Schüpbach and Roth, 1994 ). In Bic-D mom egg chambers, the posterior displacement of the oocyte and grk signal correlates with a posterior shift in expression of the dorsal/anterior columnar follicle cell marker BB142, and this also correlates...

... depleted in larvae, the resulting adult phenotypes demonstrate that RLC is required in a stage-specific fashion for proper development of eye and leg imaginal discs. When RLC is depleted in adult females, oogenesis is reversibly disrupted. Without RLC induction, developing egg chambers display a succession...