..., narrowing of both vegetative and floral organs, reduction in carpel size and fertility and delayed germination. The petaloid first whorl results from ectopic expression of the class B genes DEFICIENS and GLOBOSA and is correlated with the ectopic expression of the proposed class B/C gene regulator FIMBRIATA...

... and morphogenesis of the vertebrate inner ear. Using a novel technique for gene transfer into chicken embryos, we have readdressed the role of FGF3 during inner ear development in avians. We find that ectopic expression of FGF3 results in the formation of ectopic placodes which express otic marker genes...

... in vertebrate development. Here we report the isolation of Ol-eng2 , a medaka fish ( Oryzias latipes ) engrailed gene. We have monitored the effects of its widespread expression following mRNA injections in 1- and 2-cell medaka and Xenopus embryos. We found that the ectopic expression of Ol-eng2 predominantly...

..., which adopted a radialized pattern. Finally, ectopic expression of Otp mRNA affected patterning along the oral-aboral axis and caused skeletal abnormalities that resembled those exhibited by nickel-treated embryos. From these results, we conclude that the Otp homeodomain gene is involved in short-range...

... inflorescences, are normally determinate structures. We show that ectopic expression of kn1 in the barley awn is sufficient to direct the development of ectopic meristems, forming inflorescence-like structures. This homeotic transformation is similar to the phenotype produced by misexpression of the barley...

... differentiation; bam mutant germ cells fail to differentiate, but instead proliferate like stem cells. This paper reports that ectopic expression of bam is sufficient to extinguish stem cell divisions. Heat-induced bam + expression specifically eliminated oogenic stem cells while somatic stem cell populations...

... for the formation of specific head segments, its ectopic expression does not disturb head development. We conclude that the spatial limits of btd expression are not instructive for metamerization of the head region and that btd activity does not contribute to a combinatorial code for specification of segment...

... consistently different levels and developmental profiles of expression. Individual lines showed specific disruptions in pair-rule patterning that were correlated with the level and timing of ectopic expression. These results suggest that the ectopic domain acts as a source for morphogenetic activity...

... that ectopic expression of either gooseberry protein causes cell fate transformations that are reciprocal to those of a gooseberry deletion mutant. Our results suggest that the gooseberry-distal protein is required for the specification of naked cuticle in the epidermis and specific neuroblasts in the central...

... abnormalities observed for embryos that have undergone ectopic expression of ttk p69. Such embryos die before hatching and do not exhibit a specific pairrule phenotype. In addition, a ttk null mutation has recently been isolated and reveals an embryoniclethal phenotype (Xiong and Montell, personal...

..., that are expressed in PS10-13 and PS14-15, respectively. Although ABD-B m and r proteins have distinct developmental functions, ectopic expression of either protein during embryogenesis induces the development of filzkörper and associated spiracular hairs, structures normally located in PS13, at ectopic sites...

... of Biologists 1992 Drosophila melanogaster wingless ectopic expression segmentation Five hours after fertilization, the Drosophila embryo exhibits the first morphological signs of repeated units that will form the segments of the larva and adult fruit fly (reviewed by Lawrence, 1992...

... genes have specific roles in establishing the correct spatial patterns of sensory organs in their normal domains of expression. In addition, we also report the effects of ectopic expression of the homeotic genes labial (lab), Deformed (Dfd), Scr, Antp or Ubx on the normal development of sensory organs...

... ommatidia. This pattern is conserved in a significantly diverged Drosophila species. We show that, surprisingly, ommatidia formed by homozygous hairy - mutant clones are apparently normal, indicating that hairy function in the eye is dispensable. However, we do find that ectopic expression of hairy causes...

...Marek Mlodzik; Greg Gibson; Walter J. Gehring ABSTRACT The effects of heat-shock-induced ectopic expression of the homeobox gene caudal (cad) at all stages of Drosophila development have been examined. Presence of cad protein (CAD) at the anterior end of cellular blastoderm embryos was found...

... stages, embryos show a bifurcation of their anterior neural tube as a result of the duplication of the embryonic axis ( Fig. 7 ). Therefore, ectopic expression of int-1 seems to interfere with the machinery for axial specification, which normally produces only one embryonic axis. This result...

... using an inducible promoter, can lead to alterations of segmental identity. In this report, we present the consequences of ectopic expression of the Antennapedia gene under the control of a heat-shock promoter, at distinct stages throughout Drosophila development. In young embryos, up to the stage...