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Keywords: doublesex
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Journal Articles
Journal: Development
Development (2019) 146 (16): dev175158.
Published: 22 August 2019
...Neha Ghosh; Asif Bakshi; Risha Khandelwal; Sriivatsan Govinda Rajan; Rohit Joshi ABSTRACT Highly conserved DM domain-containing transcription factors (Doublesex/MAB-3/DMRT1) are responsible for generating sexually dimorphic features. In the Drosophila central nervous system, a set of Doublesex (Dsx...
Includes: Supplementary data
Journal Articles
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Reproductive biology
Journal: Development
Development (2019) 146 (14): dev178285.
Published: 25 July 2019
... traits are controlled by sex-specific isoforms of the doublesex ( dsx ) transcription factor, and dsx expression is mostly limited to cells that give rise to sexually dimorphic traits. However, it is unknown how this mosaic of sexually dimorphic and monomorphic organs arises. Here, we characterize...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (11): dev170001.
Published: 10 June 2019
...Nicole Camara; Cale Whitworth; Abigail Dove; Mark Van Doren ABSTRACT Sex-specific development of the gonads is a key aspect of sexual dimorphism that is regulated by Doublesex/Mab3-related transcription factors (DMRTs) in diverse animal species. We find that in mutants for Drosophila dsx...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (8): 1830–1842.
Published: 15 April 2013
... product of the gene doublesex promotes programmed cell death of these neuroblasts in females, and is needed for their survival, but not proliferation, in males. These data establish the terminal neuromeres as a model for further investigations into the mechanisms controlling segment- and sex-specific...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2761–2771.
Published: 01 July 2011
...Shengzhan D. Luo; Guang W. Shi; Bruce S. Baker Uncovering the direct regulatory targets of doublesex ( dsx ) and fruitless ( fru ) is crucial for an understanding of how they regulate sexual development, morphogenesis, differentiation and adult functions (including behavior) in Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (13): 2197–2203.
Published: 01 July 2010
... Brain Doublesex Nervous system To assess dmrt1 expression in ENU34 mutants, nested PCR was performed on total RNA from 40 wild-type or mutant mid-tailbud embryos using the oligonucleotides 5′-CAAGCGACAGAGGAGTTGAG-3′ and 5′-TGCCTGGTCATTACACGAAG-3′ for 20 cycles, then 5...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (20): 4661–4675.
Published: 15 October 2002
... likely to encode a transcription factor with no known DNA-binding domain, leads to the inference that ix may require the female-specific protein product of the doublesex ( dsx ) gene in order to function. Consistent with this inference, we find that for all sexually dimorphic cuticular structures...