... Dorsoventral patterning Neurogenesis Single cell RNA sequencing Hindbrain boundary Fgf signalling Cancer Research UK 10.13039/501100000289 FC001217 Medical Research Council 10.13039/501100000265 FC001217 Wellcome Trust 10.13039/100010269 FC001217...

...-dependent suppression of developmental patterning factors such as Pax6 and Gsx2. LGE Cerebral cortex Dorsoventral patterning Neural progenitor Neurogenesis Olfactory bulb Mouse Ministry of Education, Culture, Sports, Science and Technology 10.13039/501100001700 JP22700361...

... of the first cleavage results in embryonic ventralisation, but removal of this part at the two-cell stage leads to embryonic dorsalisation. How this is achieved remains unknown. Here, we report a novel mode of maternal regulation of BMP signalling during dorsoventral patterning in zebrafish. We identify Vrtn...

... of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Highlighted article: Oxygen-sensitive hydroxylases regulate HIFα, and consequently nodal , asymmetry in the prospective dorsal and ventral blastula, providing positional bias for dorsoventral patterning. Hypoxia HIFα...

... in distinct regions of the pharyngeal arches illuminates the roles of Edn1 and Jagged-Notch signaling and identifies novel domain-specific genes in craniofacial patterning. Craniofacial Zebrafish Jaw Skeleton Cartilage Bone Cranial neural crest Dorsoventral patterning Endothelin Edn1 Jagged...

...: Bucky ball is essential for germ plasm assembly in zebrafish. It binds Kinesin-1, which promotes microtubule reorganisation after egg activation and is required for Bucky ball activity. Bucky ball Kinesin-1 Germ plasm Dorsoventral patterning Germ cell Maternal In sexually reproducing...

... patterning in the eye imaginal disc and regulates expression of the polarity protein four-jointed . Eye Retina Dorsoventral patterning Extra macrochaetae Notch Four-jointed Complex organs such as the mammalian retina are composed of several distinct functional units and hundreds...

... in the zebrafish alters the fate of the mandibular arch neural crest and phenocopies a retinoic acid-induced phenotype . Development 122 , 735 – 746 . Dick A. , Meier A. , Hammerschmidt M. ( 1999 ). Smad1 and Smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo...

.... Published by The Company of Biologists Ltd 2013 Dorsoventral patterning Modularity Somite Zic Oryzias latipes Vertebrates display diverse morphology and coloration, especially on the dorsal side. For example, many of reptiles and fish have crests or fins on the midline...

... statement The authors declare no competing financial interests. 4 7 2012 © 2012. Microtubule dynamics Polarity Embryonic axes Dorsoventral patterning Cortical rotation wnt8a RNA Zebrafish In many animals, embryonic axis formation requires polarized...

... ; Moussian and Roth, 2005 ; Zhang et al., 2009 ). Dorsoventral patterning EGFR signaling pipe Mirror Capicua Drosophila © 2012. 6 1 2012 Competing interests statement The authors declare no competing financial interests. * Author for correspondence...

... Dorsoventral patterning The facial skeleton develops from cranial neural crest cells (CNCCs) that populate a series of segments called the pharyngeal arches ( Platt, 1893 ). Subsequently, skeletal elements of varying morphology develop from distinct DV domains within the arches ( Crump et al., 2006...

... and posterior gap genes and may directly regulate the anterior gap gene giant . We show otd1 and hunchback also influence dorsoventral patterning by regulating zerknült ( zen ) as they do in Tribolium , but that zen does not regulate the expression of honeybee gap genes. This suggests that interactions between...

..., pdb.emo114 . Roth S. , Stein D. , Nüsslein-Volhard C. ( 1989 ). A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo . Cell 59 , 1189 - 1202 . Simanton W. , Clark S. , Clemons A. , Jacowski C...

... . We obtained a similar range of cuticle phenotypes as in previously described RNAi experiments; however, we noticed unexpected effects on blastodermal cell fates. First, we found that Tc-otd is essential for dorsoventral patterning. RNAi depletion results in lateralized embryos, a fate map change...

...-like morphologies, whereas their ventral cognates have rod-shaped morphologies. Moreover, the dorsal Op bone has a fan-shaped morphology that is distinct from the finger-shaped ventral Br bone. Jagged Notch Craniofacial Skeleton Zebrafish Dorsoventral patterning ...

.... * Authors for correspondence (e-mail: [email protected] ; [email protected] ) 31 8 2006 © 2006. 2006 CNS Brain Neuroectoderm Neuroblasts Dorsoventral patterning Cell fate vnd msh ind Glia Drosophila The Drosophila central nervous system, which can...

... of chordin . * Author for correspondence (e-mail: [email protected] ) 9 6 2006 © 2006. 2006 β-Catenin FGF signaling Dorsal axis formation Neural induction Dorsoventral patterning Anteroposterior patterning Organizer Nodal Chordin Zebrafish FGF signaling...

... as a downstream component to mediate the Sma/Mab TGFβ signaling pathway in these processes. We have discovered a new role for SMA-9 in dorsoventral patterning of the C. elegans post-embryonic mesoderm, the M lineage. In addition to a small body size, sma-9 mutant animals exhibit a dorsal-to-ventral fate...

... program. † Author for correspondence (e-mail: [email protected] ) * Present address: University of Zürich, Institute for Molecular Biology, Winterthurerstr. 190, CH 8057 Zurich, Switzerland 4 4 2006 © 2006. 2006 Zebrafish Spg Pou2 Oct4 Dorsoventral patterning Bmp...