... signaling network. BMP Cell specification Dorsal interneurons Dorsal root ganglia Melanocytes Neural crest Neural tube Notch Roof plate Single-cell RNA sequencing Quail Israel Science Foundation http://dx.doi.org/10.13039/501100003977 219/23 Zelman Cowen Academic...

... activity among proprioceptive sensory neurons innervating different targets is required for their further specification and for sensorimotor connectivity. Sensory system Sensorimotor circuit Dorsal root ganglia Neuronal specification Neurotrophins The neuromuscular circuitry that controls...

... Shox2 Dorsal root ganglia Sensory neuron Specification Fate switch Medicinska forskningsrådet 10.13039/501100006310 Knut och Alice Wallenbergs Stiftelse 10.13039/501100004063 Söderbergs Stiftelse European Research Council 10.13039/100010663...

... the sensory neurons and glia of the dorsal root ganglia (DRG). As multiple cell types are derived from this lineage, it is ideal for examining mechanisms of fate restriction during development. We have isolated a mutant, ouchless , that specifically fails to develop DRG neurons, although other NC derivatives...

...) in the zebrafish (Danio rerio , Cyprinidae) that is established within the first 2 days of embryonic development in close association with the segmentally reiterated dorsal root ganglia (DRGs). Lineage analysis and 4D in vivo imaging indicate that progeny of these embryonic MPs spread segmentally, giving rise...

... of the distribution of GFP-labeled cells as a function of electroporation (ep) stage. Note the progressive loss of labeled NC derivatives in a ventral to dorsal sequence. Ao, aorta; DRG, dorsal root ganglia; M, melanocytes; No, notochord; NT, neural tube; SG, sympathetic ganglion; VR, ventral root. Scale bar: 100 μM...

... into metameric dorsal root ganglia (DRG). By contrast, the combined loss of both guidance pathways leads to ectopic invasion of the intersomitic furrows and posterior sclerotome halves, disrupting metameric NCC streaming and DRG segmentation. The division of embryonic tissues into segments is a fundamental...

... but not cranial neural crest migration. Cell 104 , 57 -69. Ben-Zvi, A., Manor, O., Schachner, M., Yaron, A.,Tessier-Lavigne, M. and Behar, O. (2008). The Semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development. J. Neurosci. 28 , 12427 -12432. Bronner-Fraser...

... © 2003. 2003 Dorsal root ganglia Hedgehog Cyclopamine Neurogenin Neural crest Zebrafish The dorsal root ganglia (DRG) are the metamerically organized peripheral sensory ganglia important for transmitting somatosensory information from the body to the brain. The neural crest cells...

... that tissues flanking dorsal root ganglia, the notochord lying medially and the dermamyotomes lying laterally,are sources of secreted molecules that prevent axons from entering inappropriate territories. Although there is evidence suggesting that SEMA3A contributes to the repellent activity of the dermamyotome...

... in myelination. Recent expression studies suggest a role of P 0 and PMP22 not only in myelination but also during embryonic development. Here we show that, in dorsal root ganglia (DRG) and differentiated neural crest cultures, P 0 is expressed in the glial lineage whereas PMP22 is also detectable in neurons...

... © 1996 by Company of Biologists 1996 Danio rerio neural crest cell fate lateral specification dorsal root ganglia A basic premise of developmental biology is that cell fate decisions result from interplay between intrinsic factors and signals from the surrounding environment...

... and hindbrain regions. The primary defect of the exen-cephaly could be traced back to a failure to initiate neural tube closure at the midbrain-forebrain boundary. Severe malformations in the spinal cord and dorsal root ganglia were observed in the thoracic region. The spinal cord of opb mutant embryos...

...-1606(89)90072-9 Kalcheim , C. , Barde , Y. A. , Thoenen , H. and Le Douarin , N. M. (1987). In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglia . EMBO J . 6 , 2871 – 73 . 10.1002/j.1460-2075.1987.tb02589.x...

...Ronald S. Goldstein; Chaya Kalcheim ABSTRACT Metameric organization of the dorsal root ganglia (DRG) and ventral roots depends on the alternation of rostrocaudal properties within the somites. In addition, the size of DRG is likely to be regulated by the adjacent mesoderm, because unilateral...

... length of the graft. On the other hand, very small, dorsally located ganglia with irregular segmentation were seen at the level corresponding to the graft of multiple caudal halfsomites. We conclude that normal morphogenesis of dorsal root ganglia depends upon the craniocaudal integrity of the somites...

... synthesis and/or mitosis but sustained cell cycle activity and blastema development have not been achieved. Because dorsal root ganglia (DRG) implants are capable of promoting regeneration of denervated adult newt limbs (Kamrin & Singer, 1959), we have evaluated the DRG stimulation of regeneration...

.... & Peterson , E. M. (1982). Selective innervation of target regions within fetal mouse spinal cord and medulla explants by isolated dorsal root ganglia in organotypic cocultures . Devi Brain Res . 2 , 341 – 362 . 10.1016/0165-3806(81)90043-2 Dunn , G. A. (1971). Mutual contact...