... ( [email protected] ; [email protected] ) * These authors contributed equally to this work. Competing interests statement The authors declare no competing financial interests. 16 6 2011 © 2011. Mitf Dct β-Catenin Melanoblast Mouse Mice...

... directly in the developing embryo. First, we made aggregation chimaeras between transgenic Dct-lacZ and non-transgenic embryos, in which lacZ is a marker for melanoblasts. Second, we generated transgenic mice carrying a modified lacZ reporter construct containing a 289 base pair duplication ( laacZ ) under...

... or no role in wild-type fin stripe development, thus revealing a secondary mode for regulation of fin stripes. Expression of melanocyte markers in regenerating kit mutant fins suggests that kit normally acts after mitf and before dct to promote development of the primary kit -dependent melanocytes. kit...