.... We compared conserved non-coding sequences (CNCSs)between five Drosophilids along the ∼40 kb genomic locus of the RD gene dachshund ( dac ). Our analysis uncovers two separate eye enhancers in intron eight and the 3′ non-coding regions of the dac locus defined by clusters of highly conserved...

... oculis ( so ) and dachshund ( dac ) participate with these signaling molecules in a complex regulatory network that results in the initiation of eye development. Our analysis of functional relationships in the early eye disc indicates that hh and dpp play no role in regulating ey , but are required...