... filaments disrupts cellular asymmetry. These data demonstrate that the cytoskeleton reorganises during spore polarisation and controls the directed migration of the nucleus to the basal pole. The presence of the nucleus at the basal pole provides the cellular asymmetry for the asymmetric cell division...

... homology domain Cytoskeleton Cell polarity Gametogenesis Germ cell Spectraplakin Wellcome http://dx.doi.org/10.13039/100010269 080007 203144 092096 207496 Wellcome http://dx.doi.org/10.13039/100010269 Cancer Research UK http://dx.doi.org/10.13039/501100000289...

... Fuzzy controls actin polymerization and ciliogenesis via p190ARhoGAP. Planar cell polarity effectors CPLANE Primary cilium Ciliogenesis Actin Cytoskeleton ARHRhoGAP35 Mouse Canadian Institutes of Health Research http://dx.doi.org/10.13039/501100000024 CIHR230929...

... to loss of tension and changes in components at tight junctions. Toll-like receptors IRAK4 Intestinal epithelium Epithelial barrier Tight junctions Cytoskeleton Tension Medical Research Council http://dx.doi.org/10.13039/501100007155 U105178780 AstraZeneca http...

... component of supracellular actomyosin cables during epithelial morphogenesis that serve to insulate morphogenetic changes from each other. Actomyosin Supracellular cable Junctions Cytoskeleton Tension Epithelium Morphogenesis Medical Research Council http://dx.doi.org/10.13039...

... reproductive tissue architecture and fertility. Actin dynamics Capping protein Cytoskeleton Actomyosin Contractility Caenorhabditis elegans Syncytial germline Formins Arp2/3 complex Rachis Morphogenesis Cytosim Fertility Israel Science Foundation http://dx.doi.org/10.13039...

... well-studied models to other systems. LINC complex Cytoskeleton Nuclear movement Syncytia National Institute of Arthritis and Musculoskeletal and Skin Diseases http://dx.doi.org/10.13039/100000069 R56AR073193 Nuclei dynamically traversing the dense cytoplasm is a visually...

... the importance of the cytoskeleton, including actin filaments and microtubules, in rice development and environmental responses. Yet, reliable in vivo cytoskeleton markers are lacking in rice, which limits our knowledge of cytoskeletal functions in living cells. Therefore, we generated bright fluorescent marker...

...: The multinucleated embryo of the fruit fly D. melanogaster distributes nuclei with the help of centrosome-organised microtubule asters, with ordering dynamically adapting to synchronous nuclear divisions, mitotic failures and being independent of cortical actin organisation. Centrosome Cytoskeleton Force...

... of a developmental blueprint that defines the polarized organization of the apical cytoskeleton in hair cells, including stereocilia distribution and elongation. Here, we report a role for multiple PDZ domain (MPDZ) protein during apical hair cell morphogenesis in mouse. We show that MPDZ is enriched at the hair...

... morphogenesis. Branching morphogenesis Cytoskeleton Actomyosin contractility Mechanotransduction Submandibular gland The actin-myosin complex plays crucial roles in supporting various biological phenomena. The actomyosin network is first and most widely known as a functional unit for muscle...

... migration – are reviewed, with a focus on Drosophila , a powerful model for studying these events. Cell adhesion Cytoskeleton Drosophila Morphogenesis During morphogenesis, the body is assembled and remodeled by cell shape changes and movements ( Gillard and Röper, 2020 ). These events...

...-characterized regulator of mesenchymal cell adhesion signaling, F-actin cytoskeleton remodeling and single cell migration, its role in epithelial tissue organization and mammary gland morphogenesis in vivo has not been investigated. Here, using a newly developed paxillin conditional knockout mouse model...

...-microtubule interactions, ensuring proper spindle morphology and accurate chromosome movement during oocyte maturation. Oocyte Meiosis Cytoskeleton Chromosome Reproduction Bub1b National Natural Science Foundation of China 10.13039/501100001809 31771660 31401227 Fundamental...

... Paris (Programme Emergence) and the Fondation pour la Recherche Médicale (DEQ20160334869) to J.D. Deposited in PMC for release after 12 months. References Alfaro-Aco , R. and Petry , S. ( 2015 ). Building the microtubule cytoskeleton piece by piece . J. Biol. Chem.   290 , 17154...

... extension Cytoskeleton Cell protrusions Extracellular matrix Proteases Morphogenesis Wellcome Trust 10.13039/100004440 087525 Medical Research Council 10.13039/501100000265 G0801124 How the neural tube (NT) forms is a central issue in developmental biology...

... cytoskeleton in tumor cell variants exhibiting different metastatic capabilities . Cancer Res.   42 , 5183 - 5190 . Red-Horse , K. , Ueno , H. , Weissman , I. L. and Krasnow , M. A. ( 2010 ). Coronary arteries form by developmental reprogramming of venous cells . Nature   464 , 549...

... assignment. Mid1ip1l protein localizes to cortical F-actin aggregates, consistent with a direct role in cytoskeletal regulation. Our studies indicate that maternally provided aura ( mid1ip1l ) acts during the reorganization of the cytoskeleton at the egg-to-embryo transition and highlight the importance...

... ) Competing interests The authors declare no competing financial interests. 20 1 2014 14 8 2014 © 2014. Published by The Company of Biologists Ltd 2014 Axon retraction Cytoskeleton Stress fiber Synaptogenesis During neuronal development, the formation and maintenance...

... in neurons, Cdk5 controls the early phases of neuronal migration in the developing brains mainly through the regulation of microtubules and actin cytoskeleton ( Niethammer et al., 2000 ; Tanaka et al., 2004b ; Kawauchi et al., 2006 ). By contrast, migrating neurons undergo unique morphological changes...