... arrival in the posterior periplasm. A mutant phenocopy was induced in wild-type embryos that were treated with cytochalasin B or D at a very early cleavage stage. Remarkable differences were noticed in the organization of cortical F-actin between the mutants and the wild type throughout the cleavage stage...

...Jacek Kubiak; Andras Paldi; Michèle Weber; Bernard Maro ABSTRACT The microfilament inhibitor cytochalasin D inhibits extrusion of the first polar body when present during the first meiotic division of mouse oocytes; however, it does not interfere with anaphase movement of chromosomes, and thus...

... during a narrow time interval approximately three-quarters of the way through the first cell cycle. In this study, we analyze the developmental consequences of brief, cytochalasin D-induced microfilament disruption during the 1-cell stage. Our results indicate that during the first cell cycle...

... the time of exposure of oocytes to 2 h produces 76 % tripronucleate eggs. Applicability of PMA is compared with the use of cytochalasin B to induce triploidy in the mouse. 03 06 1985 Copyright © 1985 by Company of Biologists 1985 phorbol myristate acetate (PMA) fertilization mouse...