... known as Cripto), as a direct transcriptional target of MEF2C in the outflow tract via an AHF-restricted Tdgf1 enhancer. Importantly, both the MEF2C and TDGF1 genes are associated with congenital heart defects in humans. Thus, these studies establish a direct transcriptional pathway between the core...

...-CFC factor Nodal Left-right patterning Cripto XCR Xenopus Members of the EGF-CFC gene family encode small extracellular glycosylated proteins, and include Cripto and Cryptic in humans and mouse( Bamford et al., 2000 ; Ciccodicola et al., 1989 ; Dono et al., 1991...

... is essential in the establishment of the neural induction response. * Author for correspondence (e-mail: [email protected] ) 2 2 2003 © 2003. 2003 Xenopus FRL-1 EGF-CFC family cripto cryptic one-eyed pinhead Neural induction Default model Bone morphogenetic...

..., in addition, a partial activation of Nodal signalling. †Author for correspondence (e-mail: [email protected] ) 24 10 2001 © 2002. 2002 casanova Endoderm Nodal Cripto Rescue Zebrafish Endoderm gives rise to the gut, associated organs like the pancreas and the liver...

...Gabriella Minchiotti; Giuseppe Manco; Silvia Parisi; Carmine T. Lago; Frederic Rosa; M. Graziella Persico cripto is the founding member of the family of EGF-CFC genes, a class of extracellular factors essential for early vertebrate development. In this study we show that injection of Cripto...