... factor 2a (Hif2a). By Cre-lox gene excision, we show that Hif2a in retinal neuroprogenitor cells upregulates the expression of the pro-angiogenic mediators vascular endothelial growth factor and erythropoietin, whereas it locally downregulates the angiogenesis inhibitor endostatin. Importantly, absence...

... M. , Kaslin J. , Machate A. , Brand M. ( 2011 ). Generation of a non-leaky heat shock-inducible Cre line for conditional Cre/lox strategies in zebrafish . Dev. Dyn. 240 , 108 – 115 . Hulander M. , Kiernan A. E. , Blomqvist S. R. , Carlsson P...

... at high levels on neural stem cells and can be used for their selection. MAPK, but not PI3K, signalling is required for neural stem cell maintenance, as assessed by neurosphere formation, and inhibition or genetic ablation of β1 integrin using cre/lox technology reduces the level of MAPK activity. We...

... to generate a signal that is required for ventricular cardiomyocyte development and chamber maturation. * Author for correspondence (e-mail: [email protected] ) 10 03 1998 22 04 1998 © 1998 by Company of Biologists 1998 RXRα Gene targeting cre/lox Cardiogenesis Mouse Muscle...