...Shashwati Bhattacharya; Caitlin Hyland; Matthias M. Falk; M. Kathryn Iovine ABSTRACT The gap junction protein Connexin 43 (Cx43) contributes to cell fate decisions that determine the location of fin ray joints during regeneration. Here, we provide insights into how Cx43, expressed medially...

...David Y. Rhee; Xiao-Qing Zhao; Richard J. B. Francis; Guo Ying Huang; John D. Mably; Cecilia W. Lo Connexin 43 knockout (Cx43 KO) mice exhibit conotruncal malformations and coronary artery defects. We observed epicardial blisters in the Cx43 KO hearts that suggest defects in epicardial epithelial...

... and maintenance of pregnancy. Although uterine angiogenesis is known to be influenced by the steroid hormones estrogen (E) and progesterone(P), the underlying molecular pathways remain poorly understood. Here, we report that the expression of connexin 43 (Cx43), a major gap junction protein, is markedly enhanced...

...Xin Xu; Richard Francis; Chih Jen Wei; Kaari L. Linask; Cecilia W. Lo Connexin 43 knockout (Cx43α1KO) mice have conotruncal heart defects that are associated with a reduction in the abundance of cardiac neural crest cells (CNCs) targeted to the heart. In this study, we show CNCs can respond...

... (ODDD) is an autosomal dominant disorder characterized by pleiotropic developmental anomalies of the limbs, teeth, face and eyes that was shown recently to be caused by mutations in the gap junction protein alpha 1 gene ( GJA1 ), encoding connexin 43 (Cx43). In the course of performing an N-ethyl-N...

[email protected] ) 18 02 1999 06 04 1999 © 2000 by Company of Biologists 2000 Pax3 Cardiogenesis connexin 43 Cre recombinase Neural crest Mouse In birds and mammals the complex process of cardiac morphogenesis requires interactions between multiple cell types intrinsic...

... of Biologists 1992 mouse embryo gap junction connexin 43 compaction In placental mammals, gastrulation of the embryo is necessarily preceded by events that ensure the formation not only of the embryo itself, but also the structures involved in implantation and subsequent generation...