...Yuu Usui; Toshihiro Aramaki; Shigeru Kondo; Masakatsu Watanabe ABSTRACT Connexin 39.4 (Cx39.4) and connexin 41.8 (Cx41.8), two gap-junction proteins expressed in both melanophores and xanthophores, are crucial for the intercellular communication among pigment cells that is necessary for generating...

... cells to polarized and tremendously ramified cells. Connexin 30, an astroglial gap-junction channel-forming protein expressed postnatally, regulates in situ the extension and ramification of astroglial processes. However, the involvement of connexin 30 in astroglial polarization, which is known...

... neural plate cells, which are products of an FGF induction at the blastula and gastrula stages, initially express neural plate-specific genes but fail to maintain the induced state and ultimately default to epidermis. The genetic lesion in the frimousse mutant lies within a connexin gene ( cx-11...

...Chun-hong Xia; Haiquan Liu; Debra Cheung; Catherine Cheng; Eddie Wang; Xin Du; Bruce Beutler; Woo-Kuen Lo; Xiaohua Gong Different mutations of α3 connexin (Cx46 or Gja8 ) andα8 connexin (Cx50 or Gja8 ), subunits of lens gap junction channels, cause a variety of cataracts via unknown mechanisms. We...

...Pei Rong; Xin Wang; Ingrid Niesman; Ying Wu; Lucio E. Benedetti; Irene Dunia; Esther Levy; Xiaohua Gong The development of the vertebrate lens utilizes a sophisticated cell-cell communication network via gap junction channels, which are made up of at least three connexin isoforms, α8 (Cx50), α3...

...J. L. Ewart; M. F. Cohen; R. A. Meyer; G. Y. Huang; A. Wessels; R. G. Gourdie; A. J. Chin; S. M. J. Park; B. O. Lazatin; S. Villabon; C. W. Lo ABSTRACT Transgenic mice were generated containing a cytomegaloviral promoter driven construct (CMV43) expressing the gap junction polylpeptide connexin 43...

... connexins in the developing and mature rat heart . Anat. Embryol . 185 , 363 – 378 . 10.1007/BF00188548 Gourdie , R. G. C. R. ,. Green , N. J. , Severs , R. H. anderson and Thompson , R. P. ( 1993a ). Evidence for a distinct gap-junctional phenotype in ventricular conduction...

... junction intercellular communication dominant-negative mutation connexin In most animal tissues, intercellular channels present in gap junctions allow the passive diffusion of ions and small water soluble molecules from cell to cell ( Loewenstein, 1981 ). These channels are unusual...

...Boris Risek; F. George Klier; Norton B. Gilula ABSTRACT The expression of four different gap junction gene products ( α 1 , β 1 , β 2 , andβ 3 ) has been analysed during rat skin development and the hair growth cycle. Both α 1 (C×43) and β 2 (C×26) connexins were coexpressed in the undifferentiated...